Changes in CpG Methylation of the Vitellogenin 1 Promoter in Adult Male Zebrafish after Exposure to 17α-Ethynylestradiol
The instructions for analysis are described in Kolli et al. (2019) along with a sample Illumina sequence file available with a ready-to-run VirtualMachine that can also be accessed at http://toxicology.uga.edu/resources/dna_methylation_analysis/. Supporting data for sequencing and qPCR raw data are available at https://doi.org/10.5281/zenodo.8313356, sharing qPCR raw data files for the endpoint for male and female fish from CFX Manger (Ver. 3.0), qPCR quantification data, TGBS raw sequences, and a TGBS metadata file with sample information.
This dataset is associated with the following publication:
Kolli, R., T. Glenn, R. Bringolf,, W. Henderson, B. Cummings, and J. Kenneke. Changes in CpG Methylation of the Vitellogenin 1 Promoter in Adult Male Zebrafish after Exposure to 17α-Ethynylestradiol. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, USA, 43(7): 1547-1556, (2024).
Resources
3 resources available
-
https://doi.org/10.5281/zenodo.8313356
FILE -
https://toxicology.uga.edu/resources/dna_methylation_analysis/
FILE -
Supplementary.docx
APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.WORDPROCESSINGML.DOCUMENT
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Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[ "020:00" ] |
| contactPoint |
{ "fn": "John Kenneke", "hasEmail": "mailto:kenneke.john@epa.gov" } |
| description | The instructions for analysis are described in Kolli et al. (2019) along with a sample Illumina sequence file available with a ready-to-run VirtualMachine that can also be accessed at http://toxicology.uga.edu/resources/dna_methylation_analysis/. Supporting data for sequencing and qPCR raw data are available at https://doi.org/10.5281/zenodo.8313356, sharing qPCR raw data files for the endpoint for male and female fish from CFX Manger (Ver. 3.0), qPCR quantification data, TGBS raw sequences, and a TGBS metadata file with sample information. This dataset is associated with the following publication: Kolli, R., T. Glenn, R. Bringolf,, W. Henderson, B. Cummings, and J. Kenneke. Changes in CpG Methylation of the Vitellogenin 1 Promoter in Adult Male Zebrafish after Exposure to 17α-Ethynylestradiol. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, USA, 43(7): 1547-1556, (2024). |
| distribution |
[ { "title": "https://doi.org/10.5281/zenodo.8313356", "accessURL": "https://doi.org/10.5281/zenodo.8313356" }, { "title": "https://toxicology.uga.edu/resources/dna_methylation_analysis/", "accessURL": "https://toxicology.uga.edu/resources/dna_methylation_analysis/" }, { "title": "Supplementary.docx", "mediaType": "application/vnd.openxmlformats-officedocument.wordprocessingml.document", "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1531458/Supplementary.docx" } ] |
| identifier | https://doi.org/10.23719/1531458 |
| keyword |
[ "DNA methylation", "ecotoxicology", "endocrine-disrupting compounds", "estrogenic compounds", "vitellogenin", "zebrafish" ] |
| license | https://pasteur.epa.gov/license/sciencehub-license-non-epa-generated.html |
| modified | 2024-03-28 |
| programCode |
[ "020:000" ] |
| publisher |
{ "name": "U.S. EPA Office of Research and Development (ORD)", "subOrganizationOf": { "name": "U.S. Environmental Protection Agency", "subOrganizationOf": { "name": "U.S. Government" } } } |
| references |
[ "https://doi.org/10.1002/etc.5879" ] |
| rights |
null
|
| title | Changes in CpG Methylation of the Vitellogenin 1 Promoter in Adult Male Zebrafish after Exposure to 17α-Ethynylestradiol |
