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Federal
Datasets for 'Probabilistic Points of Departure and Reference Doses for Characterizing Human Noncancer and Developmental/Reproductive Effects for 10,145 Chemicals'
U.S. Environmental Protection Agency —
First, we curated and selected experimental animal toxicity data and split them into two distinct data sets covering general noncancer effects and... -
Federal
Nelms_Evaluating potential refinements to existing Thresholds of Toxicological Concern (TTC) values for environmentally-relevant compounds
U.S. Environmental Protection Agency —
The Toxic Substances Control Act (TSCA) mandates the US EPA perform risk-based prioritisation of chemicals in commerce and then, for high-priority substances, develop... -
Federal
Integrating publicly available information to screen candidates for chemical prioritization under the Reauthorized Toxic Substances Control Act: A proof of concept case study using genotoxicity and carcinogenicity
U.S. Environmental Protection Agency —
Integrating publicly available information to screen candidates for chemical prioritization under the Reauthorized Toxic Substances Control Act: A proof of concept... -
Federal
A systematic analysis of read-across within REACH registration dossiers
U.S. Environmental Protection Agency —
G. Patlewicz, P. Karamertzanis, K. Paul Friedman, M. Sannicola, I. Shah, A systematic analysis of read-across within REACH registration dossiers, Computational...