-
Federal
Consumer Product Category Database recent views
U.S. Environmental Protection Agency —
The Chemical and Product Categories database (CPCat) catalogs the use of over 40,000 chemicals and their presence in different consumer products. The chemical use... -
Federal
Exposure Forecaster recent views
U.S. Environmental Protection Agency —
The Exposure Forecaster Database (ExpoCastDB) is EPA's database for aggregating chemical exposure information and can be used to help with chemical exposure... -
Federal
Interactive Chemical Safety for Sustainablity Toxicity Forecaster Dashboard recent views
U.S. Environmental Protection Agency —
EPA researchers have been using advances in computational toxicology to address lack of data on the thousands of chemicals. EPA released chemical data on 1,800... -
Federal
ToxCast Phase I recent views
U.S. Environmental Protection Agency —
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental... -
Federal
Aggregated Computational Toxicology Online Resource recent views
U.S. Environmental Protection Agency —
Aggregated Computational Toxicology Online Resource (AcTOR) is EPA's online aggregator of all the public sources of chemical toxicity data. ACToR aggregates data from... -
Federal
Distributed Structure Searchable Toxicity recent views
U.S. Environmental Protection Agency —
The Distributed Structure Searchable Toxicity (DSSTox) online resource provides high quality chemical structures and annotations in association with toxicity data. It... -
Federal
Evaluating the utility of a high throughput thiol-containing fluorescent probe to screen for reactivity: A case study with the Tox21 library recent views
U.S. Environmental Protection Agency —
Code repository, data files, and supplementary information for "Grace Patlewicz, Katie Paul-Friedman, Keith Houck, Li Zhang, Ruili Huang, Menghang Xia, Jason Brown,... -
Federal
Saili_AOP43_Systems Modeling of Developmental Vascular Toxicity recent views
U.S. Environmental Protection Agency —
The AOP concept was used to translate ToxCast high-throughput screening data into a ToxPi matrix of 1058 chemicals x 24 features ordered by predicted potential to... -
Federal
Limited chemical structural diversity found to modulate thyroid hormone receptor in the Tox21 chemical library recent views
U.S. Environmental Protection Agency —
The Tox21 chemical library (8,305 unique structures) was screened in a quantitative high-throughput, cell-based reporter gene assay for TR agonist or antagonist... -
Federal
Structural alerts for protein binding recent views
U.S. Environmental Protection Agency —
The JRC dataset (doi: 10.1016/j.tiv.2016.07.014) includes reported outcomes in chemico, in vitro and in vivo tests for skin sensitisation. The Tox21 dataset was... -
Federal
The Tox21 10K Compound Library: Part 1 - Collaborative chemistry advancing toxicology recent views
U.S. Environmental Protection Agency —
Table S1: Tox21 IDs mapped to NCGC IDs, PubChem IDs, and DSSTox IDs, and indicating NCATS, NTP and EPA partner library associations (date stamped February 24, 2020).... -
Federal
Predicting Potential Human Health Risk with the Tox21 10k Library recent views
U.S. Environmental Protection Agency —
This study represents the first report applying IVIVE approaches and exposure comparisons using the entirety of the Tox21 federal collaboration chemical screening... -
Federal
Tox21BodyMap: A webtool to map chemical effects on the human body recent views
U.S. Environmental Protection Agency —
This manuscript describes development of a novel tool called Tox21BodyMap. This tool is designed to map biological assay data onto organs of the human body,...