24 datasets found
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Federal
MicroRNA expression of C. elegans in space environment recent views
National Aeronautics and Space Administration —
Entire microRNA expression were analyzed using the Filgen Array miRNA Caenorhabditis elegans 232 probes (Filgen). In the microRNA expression analysis we compared the... -
Federal
Gene expression profiling in human fibroblast after low-LET irradiation recent views
National Aeronautics and Space Administration —
Exposure to radiation provokes cellular responses controlled in part by gene expression networks. MicroRNAs (miRNAs) are small non-coding RNAs which mostly regulate... -
Federal
RNA-seq analysis of mycobacteria stress response to microgravity recent views
National Aeronautics and Space Administration —
The aim of this work is to determine whether mycobacteria have enhanced virulence during space travel and what mechanisms they use to adapt to microgravity. M.... -
Federal
RAD51 Interconnects Between DNA Replication DNA Repair and Immunity recent views
National Aeronautics and Space Administration —
RAD51 a multifunctional protein plays a central role in DNA replication and homologous recombination repair and is known to be involved in cancer development. We... -
Federal
Action of microgravity on root development recent views
National Aeronautics and Space Administration —
Arabidopsis were grown on horizontal or vertical clinostat for 4 8 or 12 days. Seedlings on horizontal clinostat were in simulated microgravity and seedlings on... -
Federal
Mouse fecal microbiome after exposure to high LET radiation recent views
National Aeronautics and Space Administration —
Space travel is associated with continuous low-dose-rate exposure to high Linear Energy Transfer (LET) radiation. Pathophysiological manifestations after low-dose... -
Federal
MicroRNA expression of C. elegans in space environment recent views
National Aeronautics and Space Administration —
Entire microRNA expression were analyzed using the Filgen Array miRNA Caenorhabditis elegans 232 probes (Filgen). In the microRNA expression analysis we compared the... -
Federal
Identification of miRNAs involved in cell response to ionising radiation and modeled microgravity recent views
National Aeronautics and Space Administration —
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis... -
Federal
Action of microgravity on root development recent views
National Aeronautics and Space Administration —
Arabidopsis were grown on horizontal or vertical clinostat for 4 8 or 12 days. Seedlings on horizontal clinostat were in simulated microgravity and seedlings on... -
Federal
Transcription profiling of human peripheral blood to development gene expression signatures for practical radiation biodosimetry recent views
National Aeronautics and Space Administration —
To further development of our gene expression approach to biodosimetry we have employed whole genome microarray expression profiling as a discovery platform to... -
Federal
RNA-seq analysis of mycobacteria stress response to microgravity recent views
National Aeronautics and Space Administration —
The aim of this work is to determine whether mycobacteria have enhanced virulence during space travel and what mechanisms they use to adapt to microgravity. M.... -
Federal
Medaka Osteoclast recent views
National Aeronautics and Space Administration —
During space flight bone mineral density is decreased by the influence of osteoclast activation which molecular mechanism is expectantly investigated. In the study of... -
Federal
Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection recent views
National Aeronautics and Space Administration —
To reveal outcomes of microgravity on molecular processes within the cellular environment we have employed a mass-spectrometry based proteomics approach. Proteomics... -
Federal
Response of the EPI-200 human 3-D skin model to high and low doses of protons recent views
National Aeronautics and Space Administration —
Accumulating data suggest that the biological responses to high and low doses of radiation are qualitatively different necessitating the direct study of low dose... -
Federal
Identification of miRNAs involved in cell response to ionising radiation and modeled microgravity recent views
National Aeronautics and Space Administration —
BACKGROUND: Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis... -
Federal
Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection recent views
National Aeronautics and Space Administration —
To reveal outcomes of microgravity on molecular processes within the cellular environment we have employed a mass-spectrometry based proteomics approach. Proteomics... -
Federal
Transcription profiling of human peripheral blood to development gene expression signatures for practical radiation biodosimetry recent views
National Aeronautics and Space Administration —
To further development of our gene expression approach to biodosimetry we have employed whole genome microarray expression profiling as a discovery platform to... -
Federal
Gene expression profiling in human fibroblast after low-LET irradiation recent views
National Aeronautics and Space Administration —
Exposure to radiation provokes cellular responses controlled in part by gene expression networks. MicroRNAs (miRNAs) are small non-coding RNAs which mostly regulate... -
Federal
Transient gene expression profile changes of confluent human fibroblast cells in spaceflight recent views
National Aeronautics and Space Administration —
Microgravity or an altered gravity environment from the static 1g has been shown to influence global gene expression patterns and protein levels in cultured cells or... -
Federal
Gene expression in human peripheral blood 48 hours after exposure to ionizing radiation recent views
National Aeronautics and Space Administration —
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to...
24 datasets found