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2 datasets found

Federal

Debate: A subversive view of subsets - a dissident clinician's opinion

U.S. Department of Health & Human Services —

Clinical trialists and statisticians are very wary of subgroup analysis, for good reasons. Clinicians have to deal with situations in which subgroups of patients...
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Federal

Debate: Subgroup analyses in clinical trials: fun to look at - but don't believe them!

U.S. Department of Health & Human Services —

Analysis of subgroup results in a clinical trial is surprisingly unreliable, even in a large trial. This is the result of a combination of reduced statistical power,...
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2 datasets found

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