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3 datasets found

Federal

Pooling, meta-analysis, and the evaluation of drug safety

U.S. Department of Health & Human Services —

Background The "integrated safety report" of the drug registration files submitted to health authorities usually summarizes the rates of adverse events observed for a...
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Federal

Simpson's paradox and calculation of number needed to treat from meta-analysis

U.S. Department of Health & Human Services —

Background Calculation of numbers needed to treat (NNT) is more complex from meta-analysis than from single trials. Treating the data as if it all came from one trial...
- HTML
Federal

Meta-analysis, Simpson's paradox, and the number needed to treat

U.S. Department of Health & Human Services —

Background There is debate concerning methods for calculating numbers needed to treat (NNT) from results of systematic reviews. Methods We investigate the...
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3 datasets found

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