3 datasets found
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Federal
Evaluation of Existing QSAR Models and Structural Alerts and Development of New Ensemble Models for Genotoxicity Using a Newly Compiled Experimental Dataset
U.S. Environmental Protection Agency —
In this study, a major effort was undertaken to compile a large genotoxicity dataset (54,805 records for 9299 substances) from several public sources (e.g., TOXNET,... -
Federal
Derivation of new Threshold of Toxicological Concern values for exposure via inhalation for environmentally-relevant chemicals
U.S. Environmental Protection Agency —
An effort was made to derive new inhalation TTC values using the EPA’s Toxicity Values database, ToxValDB. A total of 4703 substances captured in ToxValDB were... -
Federal
Use of Threshold of Toxicological Concern (TTC) with High Throughput Exposure Predictions (HTE) as a Risk-Based Screening Approach to Prioritize More Than Seven Thousand Chemicals
U.S. Environmental Protection Agency —
The dataset that was evaluated in this approach was taken from Wambaugh et al [29] who filtered the Tox21 library to reflect substances with similar uses to those in...
3 datasets found