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2 datasets found

Federal

Omapatrilat normalizes renal function curve in spontaneously hypertensive rats

U.S. Department of Health & Human Services —

Background The present study was designed to analyze the chronic renal response to omapatrilat, a new vasopeptidase inhibitor, in spontaneously hypertensive rats...
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Federal

Reduced natriuretic response to acute sodium loading in COMT Gene deleted mice

U.S. Department of Health & Human Services —

Background The intrarenal natriuretic hormone dopamine (DA) is metabolised by catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO). Inhibition of COMT, as...
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2 datasets found

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