5 datasets found
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Federal
Mutational analyses of the signals involved in the subcellular location of DSCR1
U.S. Department of Health & Human Services —
Background Down syndrome is the most frequent genetic disorder in humans. Rare cases involving partial trisomy of chromosome 21 allowed a small chromosomal region... -
Federal
Cloning, expression and nuclear localization of human
U.S. Department of Health & Human Services —
Background Studies suggest that the related proteins nucleoplasmin and nucleophosmin (also called B23, NO38 or numatrin) are nuclear chaperones that mediate the... -
Federal
Computational prediction of membrane-tethered transcription factors
U.S. Department of Health & Human Services —
Background Sequestration of transcription factors in the membrane is emerging as an important mechanism for the regulation of gene expression. A handful of membrane-... -
Federal
Probing the importance and potential roles of the binding of the PH-domain protein Boi1 to acidic phospholipids
U.S. Department of Health & Human Services —
Background The related proteins Boi1 and Boi2, which appear to promote polarized growth in S. cerevisiae, both contain a PH (pleckstrin homology) and an SH3 (src... -
Federal
Characterization of subcellular localization and stability of a splice variant of G alpha
U.S. Department of Health & Human Services —
Background Alternative mRNA splicing of αi2, a heterotrimeric G protein α subunit, has been shown to produce an additional protein, termed sαi2. In the sαi2 splice...
5 datasets found