5 datasets found
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Federal
The relationship between the L1 and L2 domains of the insulin and epidermal growth factor receptors and leucine-rich repeat modules
U.S. Department of Health & Human Services —
Background Leucine-rich repeats are one of the more common modules found in proteins. The leucine-rich repeat consensus motif is LxxLxLxxNxLxxLxxLxxLxx- where the... -
Federal
The PRC-barrel: a widespread, conserved domain shared by photosynthetic reaction center subunits and proteins of RNA metabolism
U.S. Department of Health & Human Services —
The PRC-H β-barrel domain, a distinct cytoplasmic β-barrel domain whose fold has no close structural relationship to any other well known β-barrel domain, is the... -
Federal
Evolution of gene fusions: horizontal transfer versus independent events
U.S. Department of Health & Human Services —
Background Gene fusions can be used as tools for functional prediction and also as evolutionary markers. Fused genes often show a scattered phyletic distribution,... -
Federal
Abundant protein domains occur in proportion to proteome size
U.S. Department of Health & Human Services —
Background Conserved domains in proteins have crucial roles in protein interactions, DNA binding, enzyme activity and other important cellular processes. It will be... -
Federal
The GOLD domain, a novel protein module involved in Golgi function and secretion
U.S. Department of Health & Human Services —
Background Members of the p24 (p24/gp25L/emp24/Erp) family of proteins have been shown to be critical components of the coated vesicles that are involved in the...
5 datasets found