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2 datasets found

Federal

PKQuest: a general physiologically based pharmacokinetic model. Introduction and application to propranolol

U.S. Department of Health & Human Services —

Background A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been...
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Federal

Effects of Age and Exposure Duration on the Sensitivity of Early Life Stage Fathead Minnow (Pimephales promelas) to Waterborne Propranolol Exposure

U.S. Environmental Protection Agency —

Given that larval fish stages provide opportunities for development of stressor-selective screening level tests, this work aimed to investigate the optimal age of...
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2 datasets found

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