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2 datasets found

Federal

Phorbol ester induces elevated oxidative activity and alkalization in a subset of lysosomes

U.S. Department of Health & Human Services —

Background Lysosomes are acidic organelles that play multiple roles in various cellular oxidative activities such as the oxidative burst during cytotoxic killing. It...
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Federal

Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of K

U.S. Department of Health & Human Services —

Background Phorbol 12-myristate 13-acetate (PMA) is often used as an activating phorbol ester of protein kinase C (PKC) to investigate the roles of the kinase in...
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2 datasets found

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