Data Catalog

• Federal

  R MCSimMod Package

  U.S. Environmental Protection Agency —

  MCSimMod is a flexible and efficient R package that can be used for implementation and application of physiologically based pharmacokinetic (PBPK) and other ordinary...

  • HTML
• Federal

  PKQuest: measurement of intestinal absorption and first pass metabolism – application to human ethanol pharmacokinetics

  U.S. Department of Health & Human Services —

  Background PKQuest, a new physiologically based pharmacokinetic (PBPK) program, is applied to human ethanol data. The classical definition of first pass metabolism...

  • HTML
• Federal

  PKQuest: a general physiologically based pharmacokinetic model. Introduction and application to propranolol

  U.S. Department of Health & Human Services —

  Background A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been...

  • HTML
• Federal

  PKQuest: volatile solutes – application to enflurane, nitrous oxide, halothane, methoxyflurane and toluene pharmacokinetics

  U.S. Department of Health & Human Services —

  Background The application of physiologically based pharmacokinetic models (PBPK) to human studies has been limited by the lack of the detailed organ information that...

  • HTML
• Federal

  PBPK Model Template Timing Source Code

  U.S. Environmental Protection Agency —

  The data set includes source code for a "PBPK model template" that can be used to implement physiologically based pharmacokinetic (PBPK) models with various different...

  • ZIP

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