12 datasets found
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Federal
PBPK Model Template Extension to VOCs
U.S. Environmental Protection Agency —
The data set includes source code that implements a PBPK model template that has been extended with features capable of implementing models for volatile organic... -
Federal
Database of congener-specific half-lives of polychlorinated biphenyls
U.S. Environmental Protection Agency —
Polychlorinated biphenyls (PCBs) are a group of 209 chemicals with varying chlorine substitutions that influence their absorption, distribution, metabolism, and... -
Federal
Source Code - Characterizing Variability and Uncertainty for Parameter Subset Selection in PBPK Models
U.S. Environmental Protection Agency —
Source Code for the manuscript "Characterizing Variability and Uncertainty for Parameter Subset Selection in PBPK Models" -- This R code generates the results... -
Federal
A Biologically Based Model to Quantitatively Assess the Role of the Nuclear Receptors liver X (LXR), and pregnane X (PXR) on Chemically Induced Hepatic Steatosis
U.S. Environmental Protection Agency —
The data used in this manuscript came from published literature. This dataset is associated with the following publication: Bay, C., and H. El-Masri. A biologically... -
Federal
HTTK R Package v1.4 - JSS Article on HTTK: R Package for High-Throughput Toxicokinetics
U.S. Environmental Protection Agency —
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from... -
Federal
Source Code for Evaluating Impact of Anatomical and Physiological Variability on Human Equivalent Doses Using PBPK Models
U.S. Environmental Protection Agency —
The dataset includes source code that was used to perform analyses described in the manuscript "Evaluating Impact of Anatomical and Physiological Variability on Human... -
Federal
PBPK_modeloutputs_readme
U.S. Environmental Protection Agency —
Contains values from pbpk models for each study on n-butanol effects. This dataset is associated with the following publication: Segal, D., A. Bale, L. Phillips, A.... -
Federal
HTTK R Package v1.0
U.S. Environmental Protection Agency —
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from... -
Federal
Cross species extrapolation of the disruption of thyroid hormone synthesis by oxyfluorfen using in vitro data, physiologically based pharmacokinetic (PBPK), and thyroid hormone kinetics models
U.S. Environmental Protection Agency —
How to access data for "Decrane R, Stoker T, Murr A, Ford J, El-Masri H. Cross species extrapolation of the disruption of thyroid hormone synthesis by oxyfluorfen... -
Federal
In vivo plasma concentration for lindane after 6 hour exposure in human skin
U.S. Environmental Protection Agency —
Dataset is a time course description of lindane disappearance in blood plasma after dermal exposure in human volunteers. This dataset is associated with the following... -
Federal
Identification of differentially expressed genes and networks related to hepatic lipid dysfunction
U.S. Environmental Protection Agency —
Jaleh A. Abedini, Sakshi Handa, Stephen Edwards, Brian Chorley, Hisham El-Masri, Identification of differentially expressed genes and networks related to hepatic...
12 datasets found