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Federal
Dynamic nature of epigenetic patterns observed during the Mars 520-d mission simulation recent views
National Aeronautics and Space Administration —
Interplanetary human spaceflight represents a formidable medical challenge but also provides a unique platform for investigating human adaptation to extreme... -
Federal
Effect of a 91 day long stay in weightlessness on the International Space Station on mouse skin physiology recent views
National Aeronautics and Space Administration —
Comparative gene expression in skin between mice maintained in microgravity (0g) and normogravity (1g) environment. Six male C57Bl/J10 mice were housed for 91 days in... -
Federal
Expression profiling of murine lung 70 days following exposure to fractionated or acute dose of 1.0 Gy 56Fe- particle irradiation recent views
National Aeronautics and Space Administration —
Irradiation of the K-rasLA1 mouse model with a fractionated dose of 1.0Gy 56Fe- particles increases the incidence of invasive carcinoma compared to unirradiated... -
Federal
The Role of PTHrP in Osteoblast Response to Microgravity: Implications for Osteoporosis Development. recent views
National Aeronautics and Space Administration —
Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients but with an accelerated timeframe. This... -
Federal
Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland recent views
National Aeronautics and Space Administration —
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation.... -
Federal
Molecular mechanism of flocculation self-recognition in yeast and its role in mating and survival recent views
National Aeronautics and Space Administration —
Saccharomyces cerevisiae flocculation occurs when fermentable sugars are limiting and is therefore considered as a way to enhance the survival chance of Flo-... -
Federal
Densely Ionizing Radiation Effects on the Microenvironment Promote Aggressive Trp53 Null Mammary Carcinomas recent views
National Aeronautics and Space Administration —
Densely ionizing radiation is a major component of the space radiation environment and has potentially greater carcinogenic effect compared to sparsely ionizing... -
Federal
Dynamic nature of epigenetic patterns observed during the Mars 520-d mission simulation recent views
National Aeronautics and Space Administration —
Interplanetary human spaceflight represents a formidable medical challenge but also provides a unique platform for investigating human adaptation to extreme... -
Federal
Action of microgravity on root development recent views
National Aeronautics and Space Administration —
Arabidopsis were grown on horizontal or vertical clinostat for 4 8 or 12 days. Seedlings on horizontal clinostat were in simulated microgravity and seedlings on... -
Federal
microRNA expression profiles in human peripheral blood lymphocytes cultured in modeled microgravity recent views
National Aeronautics and Space Administration —
In the present study we analyzed miRNA and mRNA expression profiles in human peripheral blood lymphocytes (PBLs) incubated in microgravity condition simulated by a... -
Federal
Microbial Observatory (ISS-MO): Draft Genome Sequence of two Aspergillus fumigatus Strains Isolated from the International Space Station recent views
National Aeronautics and Space Administration —
Aspergillus fumigatus is a saprophytic filamentous fungus that is ubiquitous outdoors (soil decaying vegetation) and indoors (hospitals simulated closed habitats... -
Federal
Effect of a 91 day long stay in weightlessness on the International Space Station on mouse skin physiology recent views
National Aeronautics and Space Administration —
Comparitive gene expression in skin between mice maintained in microgravity (0g) and normogravity (1g) environment. Six male C57Bl/J10 mice were housed for 91 days in... -
Federal
Bacillus subtilis strains at low-pressure: 5 kPa versus 101 kPa growth recent views
National Aeronautics and Space Administration —
Comparing the transcriptional responses of Bacillus subtilis strains WN624 and WN1106 at 5 kPa and 101 kPa. WN1106 is a 5 kPa-evolved strain with increased fitness... -
Federal
Gene expression profiling of human peripheral blood lymphocytes cultured in modeled microgravity recent views
National Aeronautics and Space Administration —
In the present study we analyzed miRNA and mRNA expression profiles in human peripheral blood lymphocytes (PBLs) incubated in microgravity condition simulated by a... -
Federal
Spaceflight Modulates Gene Expression in Astronauts recent views
National Aeronautics and Space Administration —
Astronauts are exposed to a unique combination of stressors during spaceflight which leads to alterations in their physiology and potentially increases their... -
Federal
Bacillus subtilis strains at low-pressure: 5 kPa versus 101 kPa growth recent views
National Aeronautics and Space Administration —
Comparing the transcriptional responses of Bacillus subtilis strains WN624 and WN1106 at 5 kPa and 101 kPa. WN1106 is a 5 kPa-evolved strain with increased fitness... -
Federal
Transcriptome Profiles in Normal Human Bronchial Epithelial Cells after Exposure to gamma-rays and different HZE particles recent views
National Aeronautics and Space Administration —
Distinct transcriptome profiles in response to low-LET and high-LET and different radiation qualities of HZE particles. Total RNA obtained from HBEC3KT cells after 1... -
Federal
Gene expression in human peripheral blood 48 hours after exposure to ionizing radiation recent views
National Aeronautics and Space Administration —
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to... -
Federal
Gene expression profiles of irradiated lung tissue in three mouse strains recent views
National Aeronautics and Space Administration —
The aim of our research is to clarify the mechanisms generating heterogeneity in response to C-ion irradiation that arise from individual genetic variations in... -
Federal
Exposure of zebrafish larvae to 3g and 5g hyper gravity between 5-6 days post-fertilization. recent views
National Aeronautics and Space Administration —
The general objective of the study was to determine modulation of gene expression by environmental factors with a special emphasis on bone formation. For this reason...