6 datasets found
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Federal
Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state
U.S. Department of Health & Human Services —
Background Macrophages sense microorganisms through activation of members of the Toll-like receptor family, which initiate signals linked to transcription of many... -
Federal
Auto-protective redox buffering systems in stimulated macrophages
U.S. Department of Health & Human Services —
Background Macrophages, upon encounter with micro-organisms or stimulated by cytokines, produce various effector molecules aimed at destroying the foreign agents and... -
Federal
Activation of macrophages by silicones: phenotype and production of oxidant metabolites
U.S. Department of Health & Human Services —
Background The effect of silicones on the immune function is not fully characterized. In clinical and experimental studies, immune alterations associated with... -
Federal
Macrophages in rheumatoid arthritis
U.S. Department of Health & Human Services —
The abundance and activation of macrophages in the inflamed synovial membrane/pannus significantly correlates with the severity of rheumatoid arthritis (RA). Although... -
Federal
Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis
U.S. Department of Health & Human Services —
IL-10 is an anti-inflammatory cytokine produced in the joint in rheumatoid arthritis by macrophages and infiltrating blood lymphocytes. Regulation of its expression... -
Federal
High frequency oscillatory ventilation attenuates the activation of alveolar macrophages and neutrophils in lung injury
U.S. Department of Health & Human Services —
Background: Recent investigations have shown that leukocyte activation is involved in the pathogenesis of ventilator-associated lung injury. This study was designed...
6 datasets found