6 datasets found
-
Federal
Molecular action of methotrexate in inflammatory diseases
U.S. Department of Health & Human Services —
Despite the recent introduction of biological response modifiers and potent new small-molecule antirheumatic drugs, the efficacy of methotrexate is nearly unsurpassed... -
Federal
Bone loss: Therapeutic approaches for preventing bone loss in inflammatory arthritis
U.S. Department of Health & Human Services —
Inflammatory arthritides are commonly characterized by localized and generalized bone loss. Localized bone loss in the form of joint erosions and periarticular... -
Federal
Angiogenesis in the pathogenesis of inflammatory joint and lung diseases
U.S. Department of Health & Human Services —
This paper reviews hypotheses about roles of angiogenesis in the pathogenesis of inflammatory disease in two organs, the synovial joint and the lung.... -
Federal
The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption
U.S. Department of Health & Human Services —
The contribution of osteoclasts to the process of bone loss in inflammatory arthritis has recently been demonstrated. Studies in osteoclast biology have led to the... -
Federal
Hyposecretion of the adrenal androgen dehydroepiandrosterone sulfate and its relation to clinical variables in inflammatory arthritis
U.S. Department of Health & Human Services —
Hypothalamic–pituitary–adrenal underactivity has been reported in rheumatoid arthritis (RA). This phenomenon has implications with regard to the pathogenesis and... -
Federal
Joint-specific and systemic autoreactivity in the development of inflammatory arthritis
U.S. Department of Health & Human Services —
Joint-specific and systemic autoreactivity in the development of inflammatory arthritis
6 datasets found