-
Federal
Expression data from C. elegans recent views
National Aeronautics and Space Administration —
We used microarrays to investigate the effects of microgravity and space radiation on the genome-wide expression of the C. elegans. Three technical replicates of wild... -
Federal
Non-targeted effects of low dose ionizing radiation act via TGF-beta to promote mammary carcinogenesis recent views
National Aeronautics and Space Administration —
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4... -
Federal
Low dose ionizing radiation treated lymphoblastoid cells recent views
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 cGy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 cGy RNA is isolated and labeled using a T7... -
Federal
T Cell Activation in Microgravity Compared to 1g (Earth s) Gravity recent views
National Aeronautics and Space Administration —
This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (mg). Immunosuppression during... -
Federal
Response of human lymphoblastoid cells to activated medium recent views
National Aeronautics and Space Administration —
Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiaed cells resuspended in fresh untreated RPMI 1640 medium with cells resuspended in... -
Federal
Gene responses in mouse brain to long-term exposure to microgravity recent views
National Aeronautics and Space Administration —
The spaceflight experiment was carried out using male C57BL/10J mice (8 weeks old at launch). Wild type mice (n=3) were launched by Space Shuttle Discovery and housed... -
Federal
Gene responses in mouse brain to long-term exposure to microgravity recent views
National Aeronautics and Space Administration —
The spaceflight experiment was carried out using male C57BL/10J mice (8 weeks old at launch). Wild type mice (n=3) were launched by Space Shuttle Discovery and housed... -
Federal
Radiation responses in peripheral white blood cells of smokers and non-smokers recent views
National Aeronautics and Space Administration —
Understanding the possible impact of potential confounding factors is necessary for any approach to radiation biodosimetry. Potential confounding factors have not... -
Federal
Root transcriptome remodeling of Arabidopsis in response to high levels of magnesium sulfate recent views
National Aeronautics and Space Administration —
Martian regolith (unconsolidated surface material) is a potential medium for plant growth in bioregenerative life support systems during manned missions on Mars.... -
Federal
An environment with strong gravitational and magnetic field alterations synergizes to promote variations in Arabidopsis thaliana callus global transcriptional state recent views
National Aeronautics and Space Administration —
Using diamagnetic levitation we have exposed A. thaliana in vitro callus cultures to five environments with different levels of effective gravity (from levitation... -
Federal
Response of human lymphoblastoid cells to activated medium recent views
National Aeronautics and Space Administration —
Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiaed cells resuspended in fresh untreated RPMI 1640 medium with cells resuspended in... -
Federal
Effect of microgravity on brain gene expression in mice recent views
National Aeronautics and Space Administration —
Changes in gravitational force such as that experienced by astronauts during space flight induce a redistribution of fluids from the caudad to the cephalad portion of... -
Federal
Human skin fibroblast mitochondrial depletion 0.5 Gy alpha-particle recent views
National Aeronautics and Space Administration —
Mitochondrial DNA-depleted human skin fibroblasts (HSF rho0) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of... -
Federal
Bystander response to 2.5 Gy of protons in a human 3-dimensional skin model in 16 h after exposure recent views
National Aeronautics and Space Administration —
Bystander mechanisms that originate in the areas surrounding a tissue damage presumably play an important role participating in wound healing and tissue remodeling.... -
Federal
Low dose ionizing radiation treated lymphoblastoid cells recent views
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 Gy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 Gy RNA is isolated and labeled using a T7... -
Federal
Response of Pseudomonas aeruginosa PAO1 to low shear modeled microgravity recent views
National Aeronautics and Space Administration —
Anticipating the risk for infectious disease during space exploration and habitation is a critical factor to ensure safety health and performance of the crewmembers.... -
Federal
Microarray Profile of Gene Expression during Osteoclast Differentiation in Modeled Microgravity recent views
National Aeronautics and Space Administration —
Microgravity leads to a 10-15% loss of bone mass in astronauts during space flight. Osteoclast is the multinucleated bone resorbing cell. In this study we used NASA... -
Federal
Expression data from C. elegans recent views
National Aeronautics and Space Administration —
We used microarrays to investigate the effects of microgravity and space radiation on the genome-wide expression of the C. elegans. Three technical replicates of wild... -
Federal
Genechip analysis of bone marrow osteoprogenitors exposed to microgravity recent views
National Aeronautics and Space Administration —
In March 2006 murine Bone Marrow Stromal Cells (BMSC) were flown in the Soyuz 12S to the International Space Station to investigate the effects of microgravity on... -
Federal
IMR90 radiation bystander time-course experiment 0.5Gy alpha particle recent views
National Aeronautics and Space Administration —
The radiation bystander effect is an important component of the overall biological response of tissues and organisms to ionizing radiation. Little is known about the...