84 datasets found
-
Federal
Non-targeted effects of low dose ionizing radiation act via TGF-beta to promote mammary carcinogenesis recent views
National Aeronautics and Space Administration —
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4... -
Federal
Drosophila melanogaster gene expression changes after spaceflight. recent views
National Aeronautics and Space Administration —
Gene expression levels were determined in 3rd instar and adult Drosophila melanogaster reared during spaceflight to elucidate the genetic and molecular mechanisms... -
Federal
Woman skeletal muscle transcriptome with bed rest and countermeasures. recent views
National Aeronautics and Space Administration —
Microgravity has a dramatic impact on human physiology illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading... -
Federal
The Arabidopsis spaceflight transcriptome: a comparison of whole plants to discrete root hypocotyl and shoot responses to the orbital environment recent views
National Aeronautics and Space Administration —
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches... -
Federal
The Arabidopsis spaceflight transcriptome: a comparison of whole plants to discrete root hypocotyl and shoot responses to the orbital environment recent views
National Aeronautics and Space Administration —
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches... -
Federal
Microgravity effect on C. elegans N2/VC (CERISE 8days) recent views
National Aeronautics and Space Administration —
Microgravity effect on C. elegans gene expression was analysed by whole genome microarray. The worms were cultivated under microgravity for 8 days in the Japanese... -
Federal
Transcription profiling of Drosophila after exposure to microgravity in the International Space Station and in a microgravity simulator recent views
National Aeronautics and Space Administration —
Larvae-Pupae transition flies (Drosophila) were recovered and transport for 3 days at 12-14C to arrest development until the launch site then exposed to RT (18-20C)... -
Federal
Expression data from C. elegans recent views
National Aeronautics and Space Administration —
We used microarrays to investigate the effects of microgravity and space radiation on the genome-wide expression of the C. elegans. Three technical replicates of wild... -
Federal
Transcriptional and proteomic response of Pseudomonas aeruginosa PAO1 to spaceflight conditions involves Hfq regulation and reveals a role for oxygen recent views
National Aeronautics and Space Administration —
Characterization of bacterial behavior in the microgravity environment of spaceflight is of importance towards risk assessment and prevention of infectious disease... -
Federal
Microarray Profile of Gene Expression during Osteoclast Differentiation in Modeled Microgravity recent views
National Aeronautics and Space Administration —
Microgravity leads to a 10-15% loss of bone mass in astronauts during space flight. Osteoclast is the multinucleated bone resorbing cell. In this study we used NASA... -
Federal
Targeting myostatin/activin A protects against skeletal muscle and bone loss during spaceflight [plasma proteomics] recent views
National Aeronautics and Space Administration —
Among the physiological consequences of extended spaceflight are loss of skeletal muscle and bone mass. One signaling pathway that plays an important role in... -
Federal
Woman skeletal muscle transcriptome with bed rest and countermeasures. recent views
National Aeronautics and Space Administration —
Microgravity has a dramatic impact on human physiology illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading... -
Federal
Response of human lymphoblastoid cells to activated medium recent views
National Aeronautics and Space Administration —
Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiaed cells resuspended in fresh untreated RPMI 1640 medium with cells resuspended in... -
Federal
Transcription profiling of Drosophila after exposure to microgravity in the International Space Station and in a microgravity simulator recent views
National Aeronautics and Space Administration —
Larvae-Pupae transition flies (Drosophila) were recovered and transport for 3 days at 12-14C to arrest development until the launch site then exposed to RT (18-20C)... -
Federal
Transcription profiling by array of the response of Arabidopsis cultivar Columbia etiolated seedlings and undifferentiated tissue culture cells to the spaceflight environment recent views
National Aeronautics and Space Administration —
We address a key baseline question of whether gene expression changes are induced by the orbital environment and then we ask whether undifferentiated cells cells... -
Federal
Response of human lymphoblastoid cells to activated medium recent views
National Aeronautics and Space Administration —
Transcriptional profiling of human lymphoblastoid TK6 cells comparing mock irradiaed cells resuspended in fresh untreated RPMI 1640 medium with cells resuspended in... -
Federal
Comparison of gene expression profiles of normal human bronchial epithelial cells in 2D and 3D cultural conditions recent views
National Aeronautics and Space Administration —
The experiment is part of a project to study DNA repair process after ionizing radiation in organotypic 3-dimentional human bronchial epithlial cell culture. Human... -
Federal
Transcription profiling by array of the response of Arabidopsis cultivar Columbia etiolated seedlings and undifferentiated tissue culture cells to the spaceflight environment recent views
National Aeronautics and Space Administration —
We address a key baseline question of whether gene expression changes are induced by the orbital environment and then we ask whether undifferentiated cells cells... -
Federal
Low dose ionizing radiation treated lymphoblastoid cells recent views
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 Gy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 Gy RNA is isolated and labeled using a T7... -
Federal
Expression data from C. elegans recent views
National Aeronautics and Space Administration —
We used microarrays to investigate the effects of microgravity and space radiation on the genome-wide expression of the C. elegans. Three technical replicates of wild...
84 datasets found