5 datasets found
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Federal
Evaluation of Existing QSAR Models and Structural Alerts and Development of New Ensemble Models for Genotoxicity Using a Newly Compiled Experimental Dataset
U.S. Environmental Protection Agency —
In this study, a major effort was undertaken to compile a large genotoxicity dataset (54,805 records for 9299 substances) from several public sources (e.g., TOXNET,... -
Federal
Dataset associated with ORD-025118: Using a Gene Expression Biomarker to Identify DNA Damage-Inducing Agents in Microarray Profiles
U.S. Environmental Protection Agency —
Datasets used in ORD-025118: Using a Gene Expression Biomarker to Identify DNA Damage-Inducing Agents in Microarray Profiles. This dataset is associated with the... -
Federal
Dataset for ORD-029419: Identification of p53 Activators in a Human Microarray Compendium
U.S. Environmental Protection Agency —
The dataset contains chemicals that were predicted to activate p53 using the biomarker or using a high throughput assay for p53. This dataset is associated with the... -
Federal
Datasets used in RD-023418: Adverse Outcome Pathway-Driven Identification of Rat Hepatocarcinogens in Short-Term Assays
U.S. Environmental Protection Agency —
Datasets used in RD-023418: Adverse Outcome Pathway-Driven Identification of Rat Hepatocarcinogens in Short-Term Assays. This dataset is associated with the following... -
Federal
Integrating publicly available information to screen candidates for chemical prioritization under the Reauthorized Toxic Substances Control Act: A proof of concept case study using genotoxicity and carcinogenicity
U.S. Environmental Protection Agency —
Integrating publicly available information to screen candidates for chemical prioritization under the Reauthorized Toxic Substances Control Act: A proof of concept...
5 datasets found