8 datasets found
-
Federal
Physical mapping of genes in somatic cell radiation hybrids by comparative genomic hybridization to cDNA microarrays
U.S. Department of Health & Human Services —
Background Somatic cell mutants can be informative in the analysis of a wide variety of cellular processes. The use of map-based positional cloning strategies in... -
Federal
A hierarchical statistical model for estimating population properties of quantitative genes
U.S. Department of Health & Human Services —
Background Earlier methods for detecting major genes responsible for a quantitative trait rely critically upon a well-structured pedigree in which the segregation... -
Federal
Comparative transcription map of the
U.S. Department of Health & Human Services —
Background To support the positional cloning of the mouse mutation wobbler (wr) the corresponding regions on human Chr2p13-14 and mouse Chr11 were analyzed in detail... -
Federal
The human homologue of
U.S. Department of Health & Human Services —
Background In sporadic ovarian cancer, we have previously reported allele loss at D6S193 (62%) on chromosome 6q27, which suggested the presence of a putative tumour... -
Federal
Mapping of the Mouse Actin Capping Protein Beta Subunit Gene
U.S. Department of Health & Human Services —
Background Capping protein (CP), a heterodimer of α and β subunits, is found in all eukaryotes. CP binds to the barbed ends of actin filaments in vitro and controls... -
Federal
Molecular genetics and structural genomics of the human protein kinase C gene module
U.S. Department of Health & Human Services —
Background Protein kinase C (PKC) has become a major focus among cell biologists interested in second-messenger signal transduction and much has been learned about... -
Federal
A draft annotation and overview of the human genome
U.S. Department of Health & Human Services —
Background The recent draft assembly of the human genome provides a unified basis for describing genomic structure and function. The draft is sufficiently accurate to... -
Federal
Chromosomal mapping, gene structure and characterization of the human and murine
U.S. Department of Health & Human Services —
Background Rab GTPases are regulators of intracellular membrane traffic. The Rab27 subfamily consists of Rab27a and Rab27b. Rab27a has been recently implicated in...
8 datasets found