5 datasets found
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Federal
Isolation and characterization of new
U.S. Department of Health & Human Services —
Background Nuclear pore complexes (NPCs) are essential for facilitated, directional nuclear transport; however, the mechanism by which ~30 different nucleoporins... -
Federal
Aggregation and retention of human urokinase type plasminogen activator in the yeast endoplasmic reticulum
U.S. Department of Health & Human Services —
Background Secretion of recombinant proteins in yeast can be affected by their improper folding in the endoplasmic reticulum and subsequent elimination of the... -
Federal
Different conformations of nascent polypeptides during translocation across the ER membrane
U.S. Department of Health & Human Services —
Background In eukaryotic cells, proteins are translocated across the ER membrane through a continuous ribosome-translocon channel. It is unclear to what extent... -
Federal
ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins
U.S. Department of Health & Human Services —
Background Annotations of completely sequenced genomes reveal that nearly half of the genes identified are of unknown function, and that some belong to... -
Federal
Upregulation of the SERCA-type Ca
U.S. Department of Health & Human Services —
Background Ca2+-ATPases of endoplasmic reticulum (SERCAs) are responsible for maintenance of the micro- to millimolar Ca2+ ion concentrations within the endoplasmic...
5 datasets found