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Federal
Normalization and analysis of DNA microarray data by self-consistency and local regression
U.S. Department of Health & Human Services —
A robust semi-parametric normalization technique has been developed, based on the assumption that the large majority of genes will not have their relative expression... -
Federal
A new non-linear normalization method for reducing variability in DNA microarray experiments
U.S. Department of Health & Human Services —
A simple and robust non-linear method is presented for normalization using array signal distribution analysis and cubic splines. Both the regression and spline-based... -
Federal
Physical mapping of genes in somatic cell radiation hybrids by comparative genomic hybridization to cDNA microarrays
U.S. Department of Health & Human Services —
Background Somatic cell mutants can be informative in the analysis of a wide variety of cellular processes. The use of map-based positional cloning strategies in... -
Federal
Transcriptional programs activated by exposure of human prostate cancer cells to androgen
U.S. Department of Health & Human Services —
DNA microarrays were used to examine the temporal program of gene expression following treatment of a human prostate cancer cell line with androgen. Significant... -
Federal
Expression profiling of
U.S. Department of Health & Human Services —
A combination of linear RNA amplification and DNA microarray hybridization has allowed the determination of expression profiles of individual imaginal discs and...