Data Catalog

• Federal

  Hypothesis to explain poor outcomes in the ALLHAT and V-HeFT trials: decreased expression of heat shock proteins

  U.S. Department of Health & Human Services —

  An explanation for the higher incidence of cardiovascular disease and heart failure in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial...

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• Federal

  Implications of recent hypertension trials for the generalist physician: whom do we treat, and how?

  U.S. Department of Health & Human Services —

  The publication of the results of the Swedish Trial in Old Patients with Hypertension-2 (STOP-2) and the termination of the doxazocin arm of the Antihypertensive and...

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• Federal

  Debate: The slippery slope of surrogate outcomes

  U.S. Department of Health & Human Services —

  Surrogate outcomes are frequently used in cardiovascular disease research. A concern is that changes in surrogate markers may not reflect changes in disease outcomes....

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• Federal

  Debate: does it matter how you lower blood pressure?

  U.S. Department of Health & Human Services —

  The evidence base for drug treatment of hypertension is strong. Early trials using thiazide diuretics suggested a shortfall in prevention of coronary heart disease....

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