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3 datasets found

Federal

A revival of the B cell paradigm for rheumatoid arthritis pathogenesis?

U.S. Department of Health & Human Services —

Dominant paradigms for the understanding of rheumatoid arthritis (RA) pathogenesis have changed over the years. A predominant role of B lymphocytes, and perhaps of...
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Federal

Natural antisense RNA inhibits the expression of BCMA, a tumour necrosis factor receptor homologue.

U.S. Department of Health & Human Services —

Background BCMA (B-cell maturation) belongs to the tumour necrosis factor receptor gene family, and is specifically expressed in mature B lymphocytes. Antisense BCMA...
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Federal

B lymphocyte involvement in ankylosing spondylitis: the heavy chain variable segment gene repertoire of B lymphocytes from germinal center-like foci in the synovial membrane indicates antigen selection

U.S. Department of Health & Human Services —

The synovial membrane (SM) of affected joints in ankylosing spondylitis (AS) is infiltrated by germinal center-like aggregates (foci) of lymphocytes similar to...
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3 datasets found

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