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4 datasets found

Federal

Interleukin-4 receptor alpha gene variants and allergic disease

U.S. Department of Health & Human Services —

The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this...
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Federal

Simultaneous identification of

U.S. Department of Health & Human Services —

Background The glutathione S-transferase (GST) enzyme GSTP1 utilizes byproducts of oxidative stress. We previously showed that alleles of GSTP1 that encode the...
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Federal

The gene encoding interleukin-13: a susceptibility locus for asthma and related traits

U.S. Department of Health & Human Services —

Asthma is a complex inflammatory disorder controlled by both genetic and environmental influences. Multiple genetic analyses have identified the T helper type 2 (Th2)...
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Federal

Interactions between genes and environmental factors in asthma and atopy: new developments

U.S. Department of Health & Human Services —

Asthma and associated phenotypes are complex traits most probably caused by an interaction of multiple disease susceptibility genes and environmental factors. Major...
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4 datasets found

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