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Federal
Molecular mechanism of flocculation self-recognition in yeast and its role in mating and survival
National Aeronautics and Space Administration —
Saccharomyces cerevisiae flocculation occurs when fermentable sugars are limiting and is therefore considered as a way to enhance the survival chance of Flo-... -
Federal
The Role of PTHrP in Osteoblast Response to Microgravity: Implications for Osteoporosis Development.
National Aeronautics and Space Administration —
Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients but with an accelerated timeframe. This... -
Federal
The Role of PTHrP in Osteoblast Response to Microgravity: Implications for Osteoporosis Development.
National Aeronautics and Space Administration —
Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients but with an accelerated timeframe. This... -
Federal
Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland
National Aeronautics and Space Administration —
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body xce xb3 radiation and mammary glands were surgically removed 2-month after radiation.... -
Federal
Transcriptome Profiles in Normal Human Bronchial Epithelial Cells after Exposure to gamma-rays and different HZE particles
National Aeronautics and Space Administration —
Distinct transcriptome profiles in response to low-LET and high-LET and different radiation qualities of HZE particles. Total RNA obtained from HBEC3KT cells after 1... -
Federal
Gene expression profiles of irradiated lung tissue in three mouse strains
National Aeronautics and Space Administration —
The aim of our research is to clarify the mechanisms generating heterogeneity in response to C-ion irradiation that arise from individual genetic variations in... -
Federal
Gene expression in human peripheral blood 48 hours after exposure to ionizing radiation
National Aeronautics and Space Administration —
Analysis of human peripheral blood 48 hours after irradiation ex vivo with graded doses of gamma rays. Results have been used in building and testing classifiers to... -
Federal
Gene expression data from 4T1 irradiated tumors treated with TGFbeta blockade
National Aeronautics and Space Administration —
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this... -
Federal
Expression profiling of murine lung 70 days following exposure to fractionated or acute dose of 1.0 Gy 56Fe- particle irradiation
National Aeronautics and Space Administration —
Irradiation of the K-rasLA1 mouse model with a fractionated dose of 1.0Gy 56Fe- particles increases the incidence of invasive carcinoma compared to unirradiated... -
Federal
Worms spun in centrifuge at elevated g values
National Aeronautics and Space Administration —
Worms spun at higher than normal g values for 4 days on 20G centrifuge vs. worms kept at 1 X G. Both are mixed stage cultures. A stimulus or stress experiment design... -
Federal
Effect of electromagnetic fields on the chondrogenic differentiation under microgravity conditions
National Aeronautics and Space Administration —
A combination therapy of electromagnetic fields (EMF) and simulated microgravity (SMG) has not been examined in regenerative medicine of cartilage. In the present... -
Federal
Dynamic nature of epigenetic patterns observed during the Mars 520-d mission simulation
National Aeronautics and Space Administration —
Interplanetary human spaceflight represents a formidable medical challenge but also provides a unique platform for investigating human adaptation to extreme... -
Federal
Radiation-induced bystander effects and gene expression in cells deficient for RAD9
National Aeronautics and Space Administration —
Background: The radiation bystander response is an important component of the overall response of cells to radiation and critical to understanding health risks of... -
Federal
Gravitational signature of synchronized cell cultures in particular cell cycle stages
National Aeronautics and Space Administration —
Cell cycle and cell proliferation are decoupled under altered gravity conditions. We have previously shown that semisolid cell cultures of Arabidopsis suffer overall... -
Federal
Transcriptome Profiles in Normal Human Bronchial Epithelial Cells after Exposure to gamma-rays and different HZE particles
National Aeronautics and Space Administration —
Distinct transcriptome profiles in response to low-LET and high-LET and different radiation qualities of HZE particles. Total RNA obtained from HBEC3KT cells after 1... -
Federal
Gene expression data from 4T1 irradiated tumors treated with TGFbeta blockade
National Aeronautics and Space Administration —
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this... -
Federal
Gene expression profiling of human peripheral blood lymphocytes cultured in modeled microgravity
National Aeronautics and Space Administration —
In the present study we analyzed miRNA and mRNA expression profiles in human peripheral blood lymphocytes (PBLs) incubated in microgravity condition simulated by a... -
Federal
Effect of electromagnetic fields on the chondrogenic differentiation under microgravity conditions
National Aeronautics and Space Administration —
A combination therapy of electromagnetic fields (EMF) and simulated microgravity (SMG) has not been examined in regenerative medicine of cartilage. In the present... -
Federal
Environmental and simulation facility conditions can modulate a behavioral-driven altered gravity response of Drosophila imagoes transcriptome
National Aeronautics and Space Administration —
Genome-wide transcriptional profiling shows that reducing gravity levels in the International Space Station (ISS) causes important alterations in Drosophila gene... -
Federal
The Role of PTHrP in Osteoblast Response to Microgravity: Implications for Osteoporosis Development.
National Aeronautics and Space Administration —
Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients but with an accelerated timeframe. This...