12 datasets found
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Federal
Multiplex ELISA MTF-1 and western blot raw data
U.S. Environmental Protection Agency —
Multiplex ELisa data, MTF-1 and western blot. This dataset is associated with the following publication: Bruno, M., J. Ross, and Y. Ge. Proteomic Responses of BEAS-2B... -
Federal
Dietary antioxidants protect gut epithelial cells from oxidant-induced apoptosis
U.S. Department of Health & Human Services —
Background The potential of ascorbic acid and two botanical decoctions, green tea and cat's claw, to limit cell death in response to oxidants were evaluated in vitro.... -
Federal
Deciphering the plasma membrane hallmarks of apoptotic cells: Phosphatidylserine transverse redistribution and calcium entry
U.S. Department of Health & Human Services —
Background During apoptosis, Ca2+-dependent events participate in the regulation of intracellular and morphological changes including phosphatidylserine exposure in... -
Federal
Differential modulation of cellular death and survival pathways by conjugated bile acids
U.S. Department of Health & Human Services —
Background The liver-derived McNtcp.24 cells transport bile acids and show distinctive responses to the two classes of conjugated bile acids. Whereas taurine-... -
Federal
Di-, tri- and tetra-5'-
U.S. Department of Health & Human Services —
Background The human FHIT gene is inactivated early in the development of many human cancers and loss of Fhit in mouse predisposes to cancer while reintroduction of... -
Federal
Adverse outcome pathway
U.S. Environmental Protection Agency —
cell culture information with toxicity and proteomic changes. This dataset is associated with the following publication: VanEmon, J., P. Pan, and F. Van Breukelen.... -
Federal
Gene trapping identifies transiently induced survival genes during programmed cell death
U.S. Department of Health & Human Services —
Background The existence of a constitutively expressed machinery for death in individual cells has led to the notion that survival factors repress this machinery and,... -
Federal
Decreased expression of the mannose 6- phosphate/insulin-like growth factor-II receptor promotes growth of human breast cancer cells
U.S. Department of Health & Human Services —
Background Loss or mutation of the mannose 6-phosphate/insulin-like growth factor-II receptor (M6P/IGF2R) has been found in breast cancer. However, whether or not... -
Federal
Retroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo
U.S. Department of Health & Human Services —
Background Phosphatidylinositol-3,4,5-triphosphate (PtdInsP3) signaling is elevated in many tumors due to loss of the tumor suppressor PTEN, and leads to constitutive... -
Federal
Role of arginine and its methylated derivatives in cancer biology and treatment
U.S. Department of Health & Human Services —
Both L-arginine supplementation and deprivation influence cell proliferation. The effect of high doses on tumours is determined by the optical configuration:... -
Federal
Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown
U.S. Department of Health & Human Services —
Background A family of aspartate-specific cysteinyl proteases, named caspases, mediates programmed cell death, apoptosis. In this function, caspases are important for... -
Federal
Coordinate regulation of RARgamma2, TBP, and TAF
U.S. Department of Health & Human Services —
Background Treatment of mouse F9 embryonal carcinoma cells with all-trans retinoic acid (T-RA) induces differentiation into primitive endodermal type cells....
12 datasets found