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Federal
Low dose ionizing radiation treated lymphoblastoid cells recent views
National Aeronautics and Space Administration —
Irradiated cell lines exposed to 1-10 cGy 2 Lymphoblastoid cell lines (GM15510 and GM15036) irradiated 1 2.5 5 7.5 10 cGy RNA is isolated and labeled using a T7... -
Federal
IMR90 radiation bystander time-course experiment 0.5Gy alpha particle recent views
National Aeronautics and Space Administration —
The radiation bystander effect is an important component of the overall biological response of tissues and organisms to ionizing radiation. Little is known about the... -
Federal
Immune responses to the in vitro LPS assault engineered in the spaceflight multi-omics study recent views
National Aeronautics and Space Administration —
Microgravity alters the immune response to in vitro LPS assault engineered in spaceflight: A multi-omics study Microgravity can facilitate creation of a potent... -
Federal
Evaluation of in vitro macrophage differentiation during space flight recent views
National Aeronautics and Space Administration —
We differentiated mouse bone marrow cells in the presence of recombinant macrophage colony stimulating (rM-CSF) factor for 14 days during the flight of space shuttle... -
Federal
Transcription profiling by array of the response of Arabidopsis cultivar Columbia etiolated seedlings and undifferentiated tissue culture cells to the spaceflight environment recent views
National Aeronautics and Space Administration —
We address a key baseline question of whether gene expression changes are induced by the orbital environment and then we ask whether undifferentiated cells cells... -
Federal
Gamma radiation and HZE treatment of seedlings in Arabidopsis recent views
National Aeronautics and Space Administration —
Plants exhibit a robust transcriptional response to gamma radiation which includes the induction of transcripts required for homologous recombination and the... -
Federal
Drosophila melanogaster gene expression changes after spaceflight. recent views
National Aeronautics and Space Administration —
Gene expression levels were determined in 3rd instar and adult Drosophila melanogaster reared during spaceflight to elucidate the genetic and molecular mechanisms... -
Federal
Synergistic effects of space radiation and microgravity (miRNA WT and ced-1 mutant) recent views
National Aeronautics and Space Administration —
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still... -
Federal
Biological and Metabolic Response in STS-135 Space-flown Mouse Skin recent views
National Aeronautics and Space Administration —
Changes in gene expression profiles implicated in oxidative stress and in ECM remodeling in mouse skin were examined after space flight. The metabolic effects of... -
Federal
Immediate Transcriptional Changes in Response to High Dose Radiation Exposure recent views
National Aeronautics and Space Administration —
One of the most likely risks astronauts on long duration space missions face is exposure to ionizing radiation associated with highly energetic and charged heavy... -
Federal
Densely Ionizing Radiation Effects on the Microenvironment Promote Aggressive Trp53 Null Mammary Carcinomas recent views
National Aeronautics and Space Administration —
Densely ionizing radiation is a major component of the space radiation environment and has potentially greater carcinogenic effect compared to sparsely ionizing... -
Federal
Salmonella Typhimurium transcription profiles in space flight recent views
National Aeronautics and Space Administration —
Salmonella transcription profiles were obtained from samples flown on space shuttle mission STS-115 and compared to profiles from Salmonella grown under identical... -
Federal
Mouse muscle LC-MSMS upon weightlessness recent views
National Aeronautics and Space Administration —
Upon weightlessness and microgravity deleterious effects on the neurosensory and neurovestibular systems haematological changes and deconditioning of musculoskeletal... -
Federal
STS-135: Mouse Liver Transcriptomics using RNA-Seq recent views
National Aeronautics and Space Administration —
Female C57BL/6 mice were flown onboard STS-135 for 13 days and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in... -
Federal
Candida albicans response to spaceflight (NASA STS-115) recent views
National Aeronautics and Space Administration —
This study presents the first global transcriptional profiling and phenotypic characterization of the major human opportunistic fungal pathogen Candida albicans grown... -
Federal
Synergistic effects of space radiation and microgravity (miRNA WT and ced-1 mutant) recent views
National Aeronautics and Space Administration —
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still... -
Federal
Synergistic effects of microgravity and space radiation (Nimblegen) recent views
National Aeronautics and Space Administration —
Space radiations and microgravity both could cause DNA damage in cells but the effects of microgravity on DNA damage response to space radiations are still... -
Federal
STS-135 Liver Metabolomics recent views
National Aeronautics and Space Administration —
Mice were flown onboard STS-135 and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples were... -
Federal
STS-135 Liver Metabolomics recent views
National Aeronautics and Space Administration —
Mice were flown onboard STS-135 and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples were... -
Federal
Chronic low dose-rate versus acute ionizing radiation induced gene expression in primary derived prostate fibroblasts recent views
National Aeronautics and Space Administration —
Using a novel flood source construct we performed a direct comparison of genome-wide gene expression regulations resulting from exposure of primary human prostate...