6 datasets found
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Federal
Staphylococcal peptidoglycans induce arthritis
U.S. Department of Health & Human Services —
Staphylococcus aureus is one of the most important pathogens in septic arthritis. To analyse the arthritogenic properties of staphylococcal peptidoglycan (PGN),... -
Federal
Inflammatory microcrystals induce murine macrophage survival and DNA synthesis
U.S. Department of Health & Human Services —
The interaction of particulates with resident macrophages is a consistent feature in certain forms of crystal-induced inflammation, for example, in synovial tissues,... -
Federal
A new model for rheumatoid arthritis?
U.S. Department of Health & Human Services —
A chance observation has led to the development of a new murine model for inflammatory arthritis. Arthritis is induced, and transferred, by T-cell-dependent... -
Federal
Identification and Characterisation of the Murine Homologue of the Gene Responsible for Cystinosis,
U.S. Department of Health & Human Services —
Background Cystinosis is an autosomal recessive disorder characterised by an intralysosomal accumulation of cystine, and affected individuals progress to end-stage... -
Federal
Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4
U.S. Department of Health & Human Services —
To determine whether IL-4 is therapeutic in treating established experimental arthritis, a recombinant adenovirus carrying the gene that encodes murine IL-4 (Ad-... -
Federal
Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature
U.S. Department of Health & Human Services —
Because angiogenesis plays a major role in the perpetuation of inflammatory arthritis, we explored a method for selectively targeting and destroying new synovial...
6 datasets found