13 datasets found
-
Federal
Sildenafil (Viagra) for male erectile dysfunction: a meta-analysis of clinical trial reports
U.S. Department of Health & Human Services —
Background Evaluation of company clinical trial reports could provide information for meta-analysis at the commercial introduction of a new technology. Methods... -
Federal
Are the pneumococcal polysaccharide vaccines effective? Meta-analysis of the prospective trials
U.S. Department of Health & Human Services —
The objective was to review the evidence of effectiveness of the polyvalent polysaccharide pneumococcal vaccine from prospective properly randomised controlled trials... -
Federal
Reporting of measures of accuracy in systematic reviews of diagnostic literature
U.S. Department of Health & Human Services —
Background There are a variety of ways in which accuracy of clinical tests can be summarised in systematic reviews. Variation in reporting of summary measures has... -
Federal
Meta-analysis: Neither quick nor easy
U.S. Department of Health & Human Services —
Background Meta-analysis is often considered to be a simple way to summarize the existing literature. In this paper we describe how a meta-analysis resembles a... -
Federal
Are proton pump inhibitors the first choice for acute treatment of gastric ulcers? A meta analysis of randomized clinical trials
U.S. Department of Health & Human Services —
Background Gastric ulcers are a frequent problem in the United States. Proton pump inhibitors have been shown to increase healing rates and improve clinical symptoms.... -
Federal
Conducting systematic reviews of diagnostic studies: didactic guidelines
U.S. Department of Health & Human Services —
Background Although guidelines for critical appraisal of diagnostic research and meta-analyses have already been published, these may be difficult to understand for... -
Federal
Sensitivity of the Puget Sound ecosystem to ocean acidification using mineralogy and taxonomy as indicators (NCEI Accession 0169109)
National Oceanic and Atmospheric Administration, Department of Commerce —
This dataset contains a number of files related to a project that characterizes the sensitivity of the Puget Sound ecosystem to ocean acidification by estimating, at... -
Federal
Simpson's paradox and calculation of number needed to treat from meta-analysis
U.S. Department of Health & Human Services —
Background Calculation of numbers needed to treat (NNT) is more complex from meta-analysis than from single trials. Treating the data as if it all came from one trial... -
Federal
Pooling, meta-analysis, and the evaluation of drug safety
U.S. Department of Health & Human Services —
Background The "integrated safety report" of the drug registration files submitted to health authorities usually summarizes the rates of adverse events observed for a... -
Federal
Updating a systematic review – what difference did it make? Case study of nicotine replacement therapy
U.S. Department of Health & Human Services —
Aims To examine the effect of updating a systematic review of nicotine replacement therapy on its contents and conclusions. Methods We examined the effects of regular... -
Federal
Hormone replacement therapy and prevention of vertebral fractures: a meta-analysis of randomised trials
U.S. Department of Health & Human Services —
Background Hormone replacement therapy (HRT) is often seen as the treatment of choice for preventing fractures in women. We undertook a recent meta-analysis of... -
Federal
Ibuprofen 400 mg is effective in women, and women are well represented in trials
U.S. Department of Health & Human Services —
Background A recent article in the New Scientist argued that women were under-represented in clinical trials which, until now, had masked the finding that ibuprofen... -
Federal
Using evidence from different sources: an example using paracetamol 1000 mg plus codeine 60 mg
U.S. Department of Health & Human Services —
Background Meta-analysis usually restricts the information pooled, for instance using only randomised, double-blind, placebo-controlled trials. This neglects other...
13 datasets found