-
Federal
Gene expression neighborhoods
U.S. Department of Health & Human Services —
The finding that neighboring eukaryotic genes are often expressed in similar patterns suggests the involvement of chromatin domains in the control of genes within a... -
Federal
Improved analytical methods for microarray-based genome-composition analysis
U.S. Department of Health & Human Services —
Genome-composition analysis using microarrays can be used to categorize genes into 'present' and 'divergent' categories. This involves selecting a signal value that... -
Federal
Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application
U.S. Department of Health & Human Services —
Background A model-based analysis of oligonucleotide expression arrays we developed previously uses a probe-sensitivity index to capture the response characteristic... -
Federal
Gene-expression profile comparisons distinguish seven organs of maize
U.S. Department of Health & Human Services —
Relative mRNA levels from maize organs have been quantified by hybridization to maize arrays fabricated with 5,376 unique expressed sequence tag clones. mRNAs from... -
Federal
TheTnfrh1(Tnfrsf23) gene is weakly imprinted in several organs and expressed at the trophoblast-decidua interface
U.S. Department of Health & Human Services —
TheTnfrh1gene (gene symbolTnfrsf23) is located near one end of a megabase-scale imprinted region on mouse distal chromosome 7, about 350 kb distant from the nearest... -
Federal
Transcriptional territories in the genome
U.S. Department of Health & Human Services —
An analysis of numerous Drosophila microarray experiments reveals that the genome has many large groups of adjacent genes that are expressed similarly but are not... -
Federal
The cloning, genomic organization and tissue expression profile of the human DLG5 gene
U.S. Department of Health & Human Services —
Background Familial atrial fibrillation, an autosomal dominant disease, was previously mapped to chromosome 10q22. One of the genes mapped to the 10q22 region is... -
Federal
Vector algebra in the analysis of genome-wide expression data
U.S. Department of Health & Human Services —
Background Data from thousands of transcription-profiling experiments in organisms ranging from yeast to humans are now publicly available. How best to analyze these... -
Federal
Genomic organisation and alternative splicing of mouse and human thioredoxin reductase 1 genes
U.S. Department of Health & Human Services —
Background Thioredoxin reductase (TR) is a redox active protein involved in many cellular processes as part of the thioredoxin system. Presently there are three... -
Federal
Plant Expression Database
Department of Agriculture —
[NOTE: PLEXdb is no longer available online. Oct 2019.] PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens.... -
Federal
Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer
U.S. Department of Health & Human Services —
Background Drug resistance in breast cancer is a major obstacle to successful chemotherapy. In this study we used cDNA microarray technology to examine gene... -
Federal
Primary effect of chemotherapy on the transcription profile of AIDS-related Kaposi's sarcoma
U.S. Department of Health & Human Services —
Background Drugs & used in anticancer chemotherapy have severe effects upon the cellular transcription and replication machinery. From in vitro studies it has... -
Federal
Glucocorticoids: do we know how they work?
U.S. Department of Health & Human Services —
It is not known to what extent glucocorticoid hormones cause their anti-inflammatory actions and their undesirable side effects by the same or different molecular... -
Federal
Genomic organization and alternative splicing of the human and mouse RPTPρ genes
U.S. Department of Health & Human Services —
Background Receptor protein tyrosine phosphatase rho (RPTPρ, gene symbol PTPRT) is a member of the type IIB RPTP family. These transmembrane molecules have been... -
Federal
A transcriptional response to Wnt protein in human embryonic carcinoma cells
U.S. Department of Health & Human Services —
Background Wnt signaling is implicated in many developmental decisions, including stem cell control, as well as in cancer. There are relatively few target genes known... -
Federal
Itt1p, a novel protein inhibiting translation termination in
U.S. Department of Health & Human Services —
Background Termination of translation in eukaryotes is controlled by two interacting polypeptide chain release factors, eRFl and eRF3. eRFl recognizes nonsense codons... -
Federal
Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios
U.S. Department of Health & Human Services —
Background The power of DNA microarrays derives from their ability to monitor the expression levels of many genes in parallel. One of the limitations of such powerful... -
Federal
Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays
U.S. Department of Health & Human Services —
A cell-culture model was used to establish a profile of gene expression during the effector phase of ceramide-mediated cell death. Of the 239 genes that met the... -
Federal
Identification ofSchistosoma mansonigender-associated gene transcripts by cDNA microarray profiling
U.S. Department of Health & Human Services —
Parasitic helminths of the genusSchistosomamate, achieve sexual maturity and produce eggs in the bloodstream of their definitive hosts, and the most important... -
Federal
Design and implementation of microarray gene expression markup language (MAGE-ML)
U.S. Department of Health & Human Services —
Meaningful exchange of microarray data is currently difficult because it is rare that published data provide sufficient information depth or are even in the same...