100 datasets found
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Federal
Delayed union of femoral fractures in older rats:decreased gene expression
U.S. Department of Health & Human Services —
Background Fracture healing slows with age. While 6-week-old rats regain normal bone biomechanics at 4 weeks after fracture, one-year-old rats require more than 26... -
Federal
Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins
U.S. Department of Health & Human Services —
Background NGF exerts a variety of actions including promotion of neuronal differentiation and survival. The PC12 rat pheochromocytoma cell line has proved valuable... -
Federal
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
U.S. Department of Health & Human Services —
Using real-time reverse transcription PCR ten housekeeping genes from different abundance and functional classes in various human tissues were evaluated. The... -
Federal
Expression profiling of
U.S. Department of Health & Human Services —
A combination of linear RNA amplification and DNA microarray hybridization has allowed the determination of expression profiles of individual imaginal discs and... -
Federal
How many replicates of arrays are required to detect gene expression changes in microarray experiments? A mixture model approach
U.S. Department of Health & Human Services —
Background It has been recognized that replicates of arrays (or spots) may be necessary for reliably detecting differentially expressed genes in microarray... -
Federal
Model-based cluster analysis of microarray gene-expression data
U.S. Department of Health & Human Services —
Background Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data.... -
Federal
The dominance of the population by a selected few: power-law behaviour applies to a wide variety of genomic properties
U.S. Department of Health & Human Services —
The sequencing of genomes provides us with an inventory of the 'molecular parts' in nature, such as protein families and folds, and their functions in living... -
Federal
Gene expression neighborhoods
U.S. Department of Health & Human Services —
The finding that neighboring eukaryotic genes are often expressed in similar patterns suggests the involvement of chromatin domains in the control of genes within a... -
Federal
Plant Expression Database
Department of Agriculture —
[NOTE: PLEXdb is no longer available online. Oct 2019.] PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens.... -
Federal
Normalization and analysis of DNA microarray data by self-consistency and local regression
U.S. Department of Health & Human Services —
A robust semi-parametric normalization technique has been developed, based on the assumption that the large majority of genes will not have their relative expression... -
Federal
TheTnfrh1(Tnfrsf23) gene is weakly imprinted in several organs and expressed at the trophoblast-decidua interface
U.S. Department of Health & Human Services —
TheTnfrh1gene (gene symbolTnfrsf23) is located near one end of a megabase-scale imprinted region on mouse distal chromosome 7, about 350 kb distant from the nearest... -
Federal
Genomic approaches to research in pulmonary hypertension
U.S. Department of Health & Human Services —
Genomics, or the study of genes and their function, is a burgeoning field with many new technologies. In the present review, we explore the application of genomic... -
Federal
Transcriptional territories in the genome
U.S. Department of Health & Human Services —
An analysis of numerous Drosophila microarray experiments reveals that the genome has many large groups of adjacent genes that are expressed similarly but are not... -
Federal
The cloning, genomic organization and tissue expression profile of the human DLG5 gene
U.S. Department of Health & Human Services —
Background Familial atrial fibrillation, an autosomal dominant disease, was previously mapped to chromosome 10q22. One of the genes mapped to the 10q22 region is... -
Federal
Improved analytical methods for microarray-based genome-composition analysis
U.S. Department of Health & Human Services —
Genome-composition analysis using microarrays can be used to categorize genes into 'present' and 'divergent' categories. This involves selecting a signal value that... -
Federal
Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application
U.S. Department of Health & Human Services —
Background A model-based analysis of oligonucleotide expression arrays we developed previously uses a probe-sensitivity index to capture the response characteristic... -
Federal
Primary effect of chemotherapy on the transcription profile of AIDS-related Kaposi's sarcoma
U.S. Department of Health & Human Services —
Background Drugs & used in anticancer chemotherapy have severe effects upon the cellular transcription and replication machinery. From in vitro studies it has... -
Federal
Obtaining reliable information from minute amounts of RNA using cDNA microarrays
U.S. Department of Health & Human Services —
Background High density cDNA microarray technology provides a powerful tool to survey the activity of thousands of genes in normal and diseased cells, which helps us... -
Federal
Glucocorticoids: do we know how they work?
U.S. Department of Health & Human Services —
It is not known to what extent glucocorticoid hormones cause their anti-inflammatory actions and their undesirable side effects by the same or different molecular... -
Federal
Genomic organization and alternative splicing of the human and mouse RPTPρ genes
U.S. Department of Health & Human Services —
Background Receptor protein tyrosine phosphatase rho (RPTPρ, gene symbol PTPRT) is a member of the type IIB RPTP family. These transmembrane molecules have been...
100 datasets found