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Federal
Toxicity Reference Database 12 recent views
U.S. Environmental Protection Agency —
The Toxicity Reference Database (ToxRefDB) contains approximately 30 years and $2 billion worth of animal studies. ToxRefDB allows scientists and the interested... -
Federal
ToxCast/ToxRefDB
U.S. Environmental Protection Agency —
ToxCast is used as a cost-effective approach for efficiently prioritizing the toxicity testing of thousands of chemicals. It uses data from state-of-the-art high... -
Federal
Aggregated Computational Toxicology Online Resource
U.S. Environmental Protection Agency —
Aggregated Computational Toxicology Online Resource (AcTOR) is EPA's online aggregator of all the public sources of chemical toxicity data. ACToR aggregates data from... -
Federal
Environmental mixtures and breast cancer: identifying co-exposure patterns between understudied vs breast cancer-associated chemicals using chemical inventory informatics
U.S. Environmental Protection Agency —
All data used for these analyses are publicly available, either through CPDat, ToxRefDB, or the CompTox Chemicals Dashboard. Script associated with these analyses are... -
Federal
Reproducibility of organ-level effects in repeat dose animal studies
U.S. Environmental Protection Agency —
This work estimates benchmarks for new approach method (NAM) performance in predicting organ-level effects in repeat dose studies of adult animals based on... -
Federal
Characterizing cleft palate toxicants using ToxCast data, chemical structure, and the biomedical literature
U.S. Environmental Protection Agency —
A data set of 500 chemicals evaluated for their ability to induce cleft palate in animal prenatal developmental studies was compiled from Toxicity Reference Database... -
Federal
ToxCast/ToxRefDB
U.S. Environmental Protection Agency —
ToxCast is used as a cost-effective approach for efficiently prioritizing the toxicity testing of thousands of chemicals. It uses data from state-of-the-art high... -
Federal
The CompTox Chemistry Dashboard: a community data resource for environmental chemistry
U.S. Environmental Protection Agency —
The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content... -
Federal
Variability in in vivo studies: Defining the upper limit of performance for predictions of systemic effect levels (ORD-034452)
U.S. Environmental Protection Agency —
The data used are from curation of legacy studies and stored in ToxRefDB. This dataset is associated with the following publication: Pham, L.L., S. Watford, P.... -
Federal
Predicting_Systemic_Toxicity_Effects_ArchTox_2017_Data
U.S. Environmental Protection Agency —
In an effort to address a major challenge in chemical safety assessment, alternative approaches for characterizing systemic effect levels, a predictive model was... -
Federal
Retrospective_Mining_of_Tox_Data_Anemia_Case_Study_RegToxPharm Data
U.S. Environmental Protection Agency —
Data from a study to critically examine some of the issues of using data from ToxRefDB, a database largely composed of guideline studies for pesticidal active... -
Federal
Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes
U.S. Environmental Protection Agency —
Background: Trends in male reproductive health have been reported for increased rates of testicular germ cell tumors, low semen quality, cryptorchidism, and... -
Federal
ToxRefDB version 2.0: Improved utility for predictive and retrospective toxicology analyses
U.S. Environmental Protection Agency —
ToxRefDB comprises information from over fifty years of in vivo toxicity data. The database includes information for over 1000 chemicals, and is being used as a... -
Federal
A comparison of machine learning approaches for predicting hepatotoxicity potential using chemical structure and targeted transcriptomic data
U.S. Environmental Protection Agency —
Supplementary data for "Tia Tate, Grace Patlewicz, Imran Shah, A comparison of machine learning approaches for predicting hepatotoxicity potential using chemical... -
Federal
Quantitative Prediction of Repeat Dose Toxicity Values using GenRA
U.S. Environmental Protection Agency —
Per Imran Shah, this was the Data used in and published as supplemental material for this manuscript. Table S1. Aggregated point of departure (POD) data obtained from... -
Federal
Predict_Organ_Toxicity_ChemResTox_Data
U.S. Environmental Protection Agency —
We use a supervised machine learning strategy to systematically investigate the relative importance of study type, machine learning algorithm, and type of descriptor... -
Federal
ToxCast/ToxRefDB
U.S. Environmental Protection Agency —
ToxCast is used as a cost-effective approach for efficiently prioritizing the toxicity testing of thousands of chemicals. It uses data from state-of-the-art high...