-
Federal
Appetite suppressants and valvular heart disease – a systematic review
U.S. Department of Health & Human Services —
Background Although appetite suppressants have been implicated in the development of valvular heart disease, the exact level of risk is still uncertain. Initial... -
Federal
Comparison of various characteristics of women who do and do not attend for breast cancer screening
U.S. Department of Health & Human Services —
Background Information regarding the characteristics and health of women who do and do not attend for breast cancer screening is limited and representative data are... -
Federal
Obstructive sleep apnea and vascular disease
U.S. Department of Health & Human Services —
There is emerging evidence linking obstructive sleep apnea (OSA) to vascular disease, including hypertension. This relationship may be independent of co-morbidity,... -
Federal
Sex differences in risk factors for coronary heart disease: a study in a Brazilian population
U.S. Department of Health & Human Services —
Background In Brazil coronary heart disease (CHD) constitutes the most important cause of death in both sexes in all the regions of the country and interestingly, the... -
Federal
Should all patients receive dual chamber pacing ICDs? The rationale for the DAVID trial
U.S. Department of Health & Human Services —
All of the prospective multicenter trials that support the use of implantable defibrillators have used single chamber pacemakers/implantable cardiovertor... -
Federal
What is the optimal prophylaxis for treatment of cardiac allograft vasculopathy?
U.S. Department of Health & Human Services —
Coronary artery disease in the transplanted heart, also known as cardiac allograft vasculopathy (CAV), is one of the major causes of mortality late after... -
Federal
Hypothesis to explain poor outcomes in the ALLHAT and V-HeFT trials: decreased expression of heat shock proteins
U.S. Department of Health & Human Services —
An explanation for the higher incidence of cardiovascular disease and heart failure in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial... -
Federal
Debate: Should the elderly receive thrombolytic therapy, or primary angioplasty, for acute myocardial infarction? The case for primary angioplasty
U.S. Department of Health & Human Services —
As the population ages the number of elderly patients presenting with acute myocardial infarction (AMI) will continue to increase. There has been no head-to-head... -
Federal
Induced cytoskeletal changes in bovine pulmonary artery endothelial cells by resveratrol and the accompanying modified responses to arterial shear stress
U.S. Department of Health & Human Services —
Background Atherosclerosis and coronary heart disease (CHD) are significant contributors to morbidity and mortality in developed countries. A noted exception is the... -
Federal
Expression of monolysocardiolipin acyltransferase activity is regulated in concert with the level of cardiolipin and cardiolipin biosynthesis in the mammalian heart
U.S. Department of Health & Human Services —
Background Monolysocardiolipin acyltransferase (MLCL AT) catalyzes the acylation of monolysocardiolipin to cardiolipin in mammalian tissues. We previously reported... -
Federal
The cloning, genomic organization and tissue expression profile of the human DLG5 gene
U.S. Department of Health & Human Services —
Background Familial atrial fibrillation, an autosomal dominant disease, was previously mapped to chromosome 10q22. One of the genes mapped to the 10q22 region is... -
Federal
Effects on respiratory function of the head-down position and the complete covering of the face by drapes during insertion of the monitoring catheters in the cardiosurgical patient
U.S. Department of Health & Human Services —
Background: We evaluated the effect on the respiratory gas exchange of the 30° head-down position and the complete covering of the face by sterile drapes. These are... -
Federal
Debate: "How low should LDL cholesterol be lowered for optimum prevention of vascular disease?" Viewpoint: "Below 100 mg/dl"
U.S. Department of Health & Human Services —
Arteriosclerotic vascular disease manifests as heart disease, stroke, aortic aneurysms, and peripheral vascular disease, and is a growing problem world-wide. The... -
Federal
New immunosuppressive drugs in heart transplantation
U.S. Department of Health & Human Services —
Only a few randomized clinical trials have been performed so far in heart transplant recipients, mainly because of the relatively small number of heart transplants... -
Federal
Somatic embryogenesis, rhizogenesis, and morphinan alkaloids production in two species of opium poppy
U.S. Department of Health & Human Services —
A study of somatic embryogenesis and rhizogenesis and their influence on production of morphinan alkaloids on two species of opium poppy is presented. We identified... -
Federal
Does lindane (gamma-hexachlorocyclohexane) increase the rapid delayed rectifier outward K
U.S. Department of Health & Human Services —
Background The effects of lindane, a gamma-isomer of hexachlorocyclohexane, were studied on transmembrane potentials and currents of frog atrial heart muscle using... -
Federal
Beat-to-beat changes in stroke volume precede the general circulatory effects of mechanical ventilation: a case report
U.S. Department of Health & Human Services —
Background: The haemodynamic as well as the ventilatory consequences of mechanical ventilation can be harmful in critically ill neonates. Newly developed ventilatory... -
Federal
Early recovery of microvascular perfusion induced by t-PA in combination with abciximab or eptifibatide during postischemic reperfusion
U.S. Department of Health & Human Services —
Background GPIIb/IIIa inhibitors abciximab and eptifibatide have been shown to inhibit platelet aggregation in ischemic heart disease. Our aim was to test the... -
Federal
MCMV induces neointima in IFN-γR-/- mice: Intimal cell apoptosis and persistent proliferation of myofibroblasts
U.S. Department of Health & Human Services —
Background CMV infections have been linked to vasculopathies like atherosclerosis and Scleroderma. CMV infects vascular endothelium with intermittent shedding of the... -
Federal
Simultaneous intra/extravascular administration of antiproliferative agents as a new strategy to inhibit restenosis: The peak of reactive cell proliferation as a hallmark for the duration of the treatment
U.S. Department of Health & Human Services —
Background Strictly intravascular approaches for the treatment of postangioplasty restenosis are effective in the intima and the inner parts of the media but may be...