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Federal
Microbiological and nutritional analysis of lettuce crops grown on the International Space Station-VEG01A
National Aeronautics and Space Administration —
The ability to grow safe, fresh food to supplement packaged foods of astronauts in space has been an important goal for NASA. Food crops grown in space experience... -
Federal
Approaches for Surveying Cosmic Radiation Damage in Large Populations of Arabidopsis thaliana Seeds- an Antarctic Example
National Aeronautics and Space Administration —
The Cosmic Ray Exposure Sequencing Science (CRESS) payload system is a proof of concept experiment to assess the genomic impact of space radiation on seeds. CRESS was... -
Federal
Exposure to elevated relative humidity in laboratory chambers alters fungal gene expression in dust from the International Space Station (ISS)
National Aeronautics and Space Administration —
Microbes are present in all occupied indoor environments, including the International Space Station (ISS). An unexpected ventilation system failure may lead to... -
Federal
Root transcriptome remodeling of Arabidopsis in response to high levels of magnesium sulfate
National Aeronautics and Space Administration —
Martian regolith (unconsolidated surface material) is a potential medium for plant growth in bioregenerative life support systems during manned missions on Mars.... -
Federal
Combined space stressors induce independent behavioral deficits predicted by early peripheral blood monocytes (Behavioral Assays)
National Aeronautics and Space Administration —
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to... -
Federal
Head-Down Tilt As a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight (Subcutaneous Tissue and Subdural Space, Body Temperature and Intracranial Pressure Biotelemetry)
National Aeronautics and Space Administration —
This ground-based program was intended to address the etiology of visual system structural and functional changes observed in astronauts during both inflight and... -
Federal
Head-Down Tilt As a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight (Optic Nerve, MRI)
National Aeronautics and Space Administration —
This ground-based program was intended to address the etiology of visual system structural and functional changes observed in astronauts during both inflight and... -
Federal
Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target (Tibialis Anterior, RR9, Western Blot)
National Aeronautics and Space Administration —
We examined the effects of ~30 days of spaceflight on glycogen synthase kinase 3 (GSK3) content and inhibitory serine phosphorylation in murine muscle and bone... -
Federal
Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight from RR-1 and RR-9 (calcium uptake and Western blot in soleus and tibialis anterior)
National Aeronautics and Space Administration —
It is well established that microgravity exposure causes significant muscle weakness and atrophy via muscle unloading. On Earth, muscle unloading leads to a... -
Federal
Specific Host Metabolite and Gut Microbiome Alterations Are Associated with Bone-loss During Spaceflight
National Aeronautics and Space Administration —
Understanding the axis of the human microbiome and physiological homeostasis is an essential task in managing deep-space travel associated health risks. The NASA led... -
Federal
37-Day microgravity exposure in 16-Week female C57BL/6J mice during the NASA Rodent Research 1 mission is associated with bone loss specific to weight-bearing skeletal sites (femur and vertebrae, micro computed tomography)
National Aeronautics and Space Administration —
Exposure to weightlessness in microgravity and elevated space radiation are associated with rapid bone loss in mammals, but questions remain about their mechanisms of... -
Federal
Predicting how varying moisture conditions impact the microbiome of dust collected from the International Space Station (ISS)
National Aeronautics and Space Administration —
On Earth, people spend 90% of their time indoors where dust and moisture can facilitate rapid microbial growth, especially fungi. The International Space Station is a... -
Federal
Head-Down Tilt As a Model for Intracranial and Intraocular Pressures, and Retinal Changes during Spaceflight (Eye, MRI, Optical Coherence Tomography, Tonometry, A-scan)
National Aeronautics and Space Administration —
This ground-based program was intended to address the etiology of visual system structural and functional changes observed in astronauts during both inflight and... -
Federal
Space environmental factor impacts upon murine colon microbiota and mucosal homeostasis
National Aeronautics and Space Administration —
We report how high and low linear energy transfer (LET) radiation, microgravity, and elevated dietary iron affect colon microbiota (determined by 16S rDNA... -
Federal
Elevated plus-maze performance of Fischer-344 rats as a function of age and of exposure to 56Fe particles
National Aeronautics and Space Administration —
The aging process is characterized by a series of changes in neurochemical functioning and in motor and cognitive performance. In addition to changes in... -
Federal
Microbiological and nutritional analysis of lettuce crops grown on the International Space Station-VEG03A
National Aeronautics and Space Administration —
The ability to grow safe, fresh food to supplement packaged foods of astronauts in space has been an important goal for NASA. Food crops grown in space experience... -
Federal
Effects of photon irradiation in the presence and absence of hindlimb unloading on the behavioral performance and metabolic pathways in the plasma of Fischer rats
National Aeronautics and Space Administration —
The space environment astronauts experience during space missions consists of multiple environmental challenges, including microgravity. In this study, we assessed... -
Federal
The impact of deep space radiation on cognitive performance: From biological sex to biomarkers to countermeasures (Elevated Plus Maze, Novel Object Recognition, Open Field, Radial Arm Water Maze, and Three Chamber Social Isolation/Interaction)
National Aeronautics and Space Administration —
In the coming decade, astronauts will travel back to the moon in preparation for future Mars missions. Exposure to galactic cosmic radiation (GCR) is a major obstacle... -
Federal
Microbiomes of the Dust Particles Collected from the International Space Station and Spacecraft Assembly Facilities
National Aeronautics and Space Administration —
The safety of the International Space Station (ISS) crewmembers and maintenance of ISS hardware are the primary rationale for monitoring microorganisms in this closed...