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Federal
Bulk RNA sequencing and spatially resolved transcriptional profiling of cerebellums from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Drosophila parasitoids go to space: Unexpected and differential effects of spaceflight on hosts and their parasitoids - Wasp Leptopilina heterotoma 14 data
National Aeronautics and Space Administration —
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are... -
Federal
Transcriptional profiling of roots and shoots from Brachypodium distachyon seedlings flown on the ISS
National Aeronautics and Space Administration —
Most major cereal grain crops are monocots. Yet, most investigations of plant adaptation to the spaceflight environment have been carried out on the dicotyledonous... -
Federal
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Cerebral Cortex
National Aeronautics and Space Administration —
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how... -
Federal
RNA-Seq analysis identifies potential modulators of gravity response in Ceratopteris spores: Evidence for modulation by calcium pumps and apyrase activity
National Aeronautics and Space Administration —
Gravity regulates the magnitude and direction of a trans-cell calcium current in germinating spores of Ceratopteris richardii. Blocking this current with nifedipine... -
Federal
Proton Irradiation Impacts Age Driven Modulations of Cancer Progression Influenced by Immune System Transcriptome Modifications from Splenic Tissue
National Aeronautics and Space Administration —
Age plays a crucial role in the interplay between tumor and host; with further perturbations induced by irradiation. Proton irradiation on tumors induces biological... -
Federal
BRIC-21 Bacillus subtilis transcriptome profile data
National Aeronautics and Space Administration —
The BRIC-21 mission was designed to identify the response of Bacillus subtilis to the human spaceflight environment. For this mission, samples were grown in rich-... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic, proteomic, epigenomic and histology data
National Aeronautics and Space Administration —
Translating fundamental biological discoveries from NASA Space Biology program into health risk from space flights has been an ongoing challenge. We propose to use... -
Federal
Effects of low dose space radiation exposures on the splenic metabolome
National Aeronautics and Space Administration —
Future space missions will include return to the Moon and long duration deep space roundtrip missions to Mars. Leaving the protection that Low Earth Orbit provides... -
Federal
Transcriptional analysis of dorsal skin from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
Reproducible changes in gut microbiome reveal a shift in microbial and host metabolism during spaceflight
National Aeronautics and Space Administration —
Data were generated as part of a NASA-funded study (Turek F (PI) et al. Effects of Spaceflight on Gastrointestinal Microbiota in Mice: Mechanisms and Impact on Multi-... -
Federal
Substrate Matters: Ionic Silver Alters Lettuce Growth, Nutrient Uptake, and Root Microbiome in a Hydroponics System
National Aeronautics and Space Administration —
Ionic silver (Ag+) is being investigated as a residual biocide for use in NASA spacecraft potable water systems on future crewed missions. This water will be used to... -
Federal
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Frontal Cortex
National Aeronautics and Space Administration —
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how... -
Federal
Drosophila parasitoids go to space: Unexpected and differential effects of spaceflight on hosts and their parasitoids - Wasp Leptopilina boulardi 17 data
National Aeronautics and Space Administration —
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are... -
Federal
Rodent Research-3-CASIS: Mouse retina transcriptomic data
National Aeronautics and Space Administration —
The Rodent Research-3 (RR-3) mission was sponsored by the pharmaceutical company Eli Lilly and Co. and the Center for the Advancement of Science in Space to study the... -
Federal
ISS Bacillus Genomes
National Aeronautics and Space Administration —
SRA of spore forming Bacillus strains isolated from various areas of the ISS during Microbial tracking investigation -
Federal
Illumina NGS RNA-seq and RRBS Sequencing on Spaceflight Mouse Retina
National Aeronautics and Space Administration —
This study was under the umbrella of the NASA Rodent Research-1 project consortium. In this project, 16-week-old female C57 BL/6J mice were sent to International... -
Federal
Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes
National Aeronautics and Space Administration —
We developed a mouse model that captures radiation effects on host biology by transplanting unirradiated Trp53 null mammary tissue to sham or irradiated hosts. Gene... -
Federal
Spaceflight and simulated microgravity conditions increase virulence of Serratia marcescens in the Drosophila melanogaster infection model
National Aeronautics and Space Administration —
While it has been shown that astronauts suffer immune disorders after spaceflight, the underlying causes are still poorly understood and there are many variables to...