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Federal
Microbiological and nutritional analysis of lettuce crops grown on the International Space Station-VEG01A
National Aeronautics and Space Administration —
The ability to grow safe, fresh food to supplement packaged foods of astronauts in space has been an important goal for NASA. Food crops grown in space experience... -
Federal
Bulk RNA sequencing and spatially resolved transcriptional profiling of cerebellums from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Fifteen days of microgravity causes growth in calvaria of mice (STS-131)
National Aeronautics and Space Administration —
Bone growth may occur in spaceflight as a response to skeletal unloading and head-ward fluid shifts. While unloading causes significant loss of bone mass and density... -
Federal
SpaceX Inspiration4 Stool Metagenome Profiling
National Aeronautics and Space Administration —
The SpaceX Inspiration4 mission was a 3-day mission with four private astronauts to low Earth orbit that occurred in September 2021. The crew collected biospecimen... -
Federal
Characterization of mouse ocular responses (Microscopy) to a 35-day (RR-9) spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations
National Aeronautics and Space Administration —
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was... -
Federal
Alternative splicing regulates the physiological adaptation of the mouse hind limb postural and phasic muscles to microgravity
National Aeronautics and Space Administration —
We sought to comprehensively elucidate the transcriptomic underpinnings of microgravity-induced muscle phenotypes in mice by evaluating both differential gene... -
Federal
Real-time quantitative PCR analysis of human cardiovascular progenitor cells flown aboard the International Space Station
National Aeronautics and Space Administration —
Adult and neonatal human cardiovacular progenitor cell clonal populations were flown aboard the ISS for 12 days prior to fixation in RNAprotect. Gene expression... -
Federal
Influence of gonadectomy on muscle health in micro- and partial-gravity environments in rats (Grip; force transducer)
National Aeronautics and Space Administration —
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle... -
Federal
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Identification of Regulatory Gene Network [iron]
National Aeronautics and Space Administration —
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1... -
Federal
Space environmental factor impacts upon murine colon microbiota and mucosal homeostasis
National Aeronautics and Space Administration —
We report how high and low linear energy transfer (LET) radiation, microgravity, and elevated dietary iron affect colon microbiota (determined by 16S rDNA... -
Federal
Metagenome profiling of feces from mice flown on the RRRM-1 mission
National Aeronautics and Space Administration —
In Rodent Research Reference Mission-1 (RRRM-1), forty female BALB/cAnNTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
Transcriptional analysis of dorsal skin from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
Microbiological and nutritional analysis of lettuce crops grown on the International Space Station-VEG03A
National Aeronautics and Space Administration —
The ability to grow safe, fresh food to supplement packaged foods of astronauts in space has been an important goal for NASA. Food crops grown in space experience... -
Federal
Densely Ionizing Radiation Effects on the Microenvironment Promote Aggressive Trp53 Null Mammary Carcinomas
National Aeronautics and Space Administration —
Densely ionizing radiation is a major component of the space radiation environment and has potentially greater carcinogenic effect compared to sparsely ionizing... -
Federal
Heart Flies - effect of microgravity on heart function in Drosophila
National Aeronautics and Space Administration —
Canton S laboratory wildtype lines (Bloomington Stock Center) and a K+ channel mutant seizure (seizurets1, a gift from Dr. Barry Ganetsky, published in Titus et al.,... -
Federal
Effects of low dose space radiation exposures on the splenic metabolome
National Aeronautics and Space Administration —
Future space missions will include return to the Moon and long duration deep space roundtrip missions to Mars. Leaving the protection that Low Earth Orbit provides... -
Federal
The impact of deep space radiation on cognitive performance: From biological sex to biomarkers to countermeasures (Flow Cytometry, Blood)
National Aeronautics and Space Administration —
In the coming decade, astronauts will travel back to the moon in preparation for future Mars missions. Exposure to galactic cosmic radiation (GCR) is a major obstacle... -
Federal
Effects of spaceflight on murine skeletal muscle gene expression
National Aeronautics and Space Administration —
Spaceflight results in a number of adaptations to skeletal muscle, including atrophy and shifts towards faster muscle fiber types. To identify changes in gene... -
Federal
The effect of spaceflight on transgenic Arabidopsis plants with compromised signaling
National Aeronautics and Space Administration —
Understanding the molecular mechanisms by which plants sense and adapt to changes in the space environment is essential for generating plants that are better adapted... -
Federal
Proteomics and Transcriptomics analysis of Arabidopsis Seedlings in Microgravity
National Aeronautics and Space Administration —
On Earth plants are constantly exposed to a gravitational field of 1G. Gravity affects a plant in every step of its development. Germinating seedlings orient their...