-
Federal
Bulk RNA sequencing and spatially resolved transcriptional profiling of cerebellums from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Alternative splicing regulates the physiological adaptation of the mouse hind limb postural and phasic muscles to microgravity
National Aeronautics and Space Administration —
We sought to comprehensively elucidate the transcriptomic underpinnings of microgravity-induced muscle phenotypes in mice by evaluating both differential gene... -
Federal
Metagenome profiling of feces from mice flown on the RRRM-1 mission
National Aeronautics and Space Administration —
In Rodent Research Reference Mission-1 (RRRM-1), forty female BALB/cAnNTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
Transcriptional analysis of dorsal skin from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
The impact of deep space radiation on cognitive performance: From biological sex to biomarkers to countermeasures (Flow Cytometry, Blood)
National Aeronautics and Space Administration —
In the coming decade, astronauts will travel back to the moon in preparation for future Mars missions. Exposure to galactic cosmic radiation (GCR) is a major obstacle... -
Federal
SpaceX Inspiration4 Stool Metagenome Profiling
National Aeronautics and Space Administration —
The SpaceX Inspiration4 mission was a 3-day mission with four private astronauts to low Earth orbit that occurred in September 2021. The crew collected biospecimen... -
Federal
SpaceX Inspiration4 Dragon Capsule Metagenomic and Metatranscriptomic Microbial Swabs
National Aeronautics and Space Administration —
The SpaceX Inspiration4 mission was a 3-day mission with four private astronauts to low Earth orbit that occurred in September 2021. The crew collected biospecimen... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse extensor digitorum longus muscle transcriptomic and epigenomic data
National Aeronautics and Space Administration —
NASA's Rodent Research (RR) project is playing a critical role in advancing biomedical research on the physiological effects of space environments. Due to the limited... -
Federal
Transcriptional analysis of liver from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
Microbial Observatory (ISS-MO): Molecular characterization of Bacillus issensis, sp. nov., isolated from various quarters of the International Space Station
National Aeronautics and Space Administration —
As part of an ongoing effort to catalogue microbial communities inhabiting the International Space Station (ISS) crew-associated environmental samples were collected... -
Federal
SpaceX Inspiration4 Oral, Nasal, and Skin Metagenomic and Metatranscriptomic Microbial Swabs
National Aeronautics and Space Administration —
The SpaceX Inspiration4 mission was a 3-day mission with four private astronauts to low Earth orbit that occurred in September 2021. The crew collected biospecimen... -
Federal
Draft Genomes of Fungi Isolated from the International Space Station during the Microbial Tracking-2 Experiment
National Aeronautics and Space Administration —
Draft genomes of fungi isolated from different surfaces on the International Space Station, as part of the Microbial Tracking 2 mission (ISS-MOP). -
Federal
RNA-seq analysis of mycobacteria stress response to microgravity
National Aeronautics and Space Administration —
The aim of this work is to determine whether mycobacteria have enhanced virulence during space travel and what mechanisms they use to adapt to microgravity. M.... -
Federal
Single cell transcriptional profiling of femur bone marrow from mice flown on Rodent Research Reference Mission-2 (RRRM-2)
National Aeronautics and Space Administration —
In the Rodent Research Reference Mission (RRRM-2), forty female C57BL/6NTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
Transcriptional analysis of colon from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
Effects of Space Flight on Inflammasome Activation in the Brain of Mice (Brain, Western Blot and ECLIA)
National Aeronautics and Space Administration —
Space exploration exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to... -
Federal
Metagenomic analysis of feces from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to... -
Federal
Evaluation of in vitro macrophage differentiation during space flight
National Aeronautics and Space Administration —
We differentiated mouse bone marrow cells in the presence of recombinant macrophage colony stimulating (rM-CSF) factor for 14 days during the flight of space shuttle... -
Federal
Bulk RNA sequencing and spatially resolved transcriptional profiling of cerebellums from mice flown on the RRRM-2 mission
National Aeronautics and Space Administration —
In the Rodent Research Reference Mission (RRRM-2), forty female C57BL/6NTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
Transcriptional analysis of spleen from mice flown on the RR-6 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-6 (RR-6) study was to evaluate muscle atrophy in mice during spaceflight and to test the efficacy of a novel therapeutic to...