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Federal
Severe community-acquired meningitis
U.S. Department of Health & Human Services —
Community-acquired meningitis is associated with high morbidity and mortality. The epidemiology of community-acquired meningitis has changed over the past 15 years... -
Federal
Incomplete gastric metaplasia in children with insulin-dependent diabetes mellitus and celiac disease. An ultrastructural study
U.S. Department of Health & Human Services —
Background The association of insulin-dependent diabetes mellitus (IDDM) and celiac disease (CD) has been widely reported in children but the relationship between the... -
Federal
Plasma colloid osmotic pressure in healthy infants
U.S. Department of Health & Human Services —
Background The plasma colloid osmotic pressure (COP) plays a major role in transcapillary fluid balance. There is no information on plasma COP of healthy infants... -
Federal
Weight loss maintenance in women two to eleven years after participating in a commercial program: a survey
U.S. Department of Health & Human Services —
Background After 5 years, most reports show that less than 10% of people maintain a 5% loss from initial body weight. Weight maintenance after 10 years is rarely... -
Federal
On the species of origin: diagnosing the source of symbiotic transcripts
U.S. Department of Health & Human Services —
Background Most organisms have developed ways to recognize and interact with other species. Symbiotic interactions range from pathogenic to mutualistic. Some... -
Federal
What can we hope to gain for trypanosomiasis control from molecular studies on tsetse biology ?
U.S. Department of Health & Human Services —
At times of crisis when epidemics rage and begin to take their toll on affected populations, as we have been witnessing with African trypanosomiasis in subSahara, the... -
Federal
Pooling, meta-analysis, and the evaluation of drug safety
U.S. Department of Health & Human Services —
Background The "integrated safety report" of the drug registration files submitted to health authorities usually summarizes the rates of adverse events observed for a... -
Federal
Compulsive checking behavior of quinpirole-sensitized rats as an animal model of Obsessive-Compulsive Disorder(OCD): form and control
U.S. Department of Health & Human Services —
Background A previous report showed that the open field behavior of rats sensitized to the dopamine agonist quinpirole satisfies 5 performance criteria for compulsive... -
Federal
Organization specific predictors of job satisfaction: findings from a Canadian multi-site quality of work life cross-sectional survey
U.S. Department of Health & Human Services —
Background Organizational features can affect how staff view their quality of work life. Determining staff perceptions about quality of work life is an important... -
Federal
Time course of muscle soreness following different types of exercise
U.S. Department of Health & Human Services —
Background Post-exercise muscle soreness is a dull, aching sensation that follows unaccustomed muscular exertion. Primarily on the basis of previous laboratory-based... -
Federal
Drug-induced and postnatal hypothyroidism impairs the accumulation of diacylglycerol in liver and liver cell plasma membranes
U.S. Department of Health & Human Services —
Background Thyroid hormones are well known modulators of signal transduction. The effect of hyper- and hypo-thyroidism on diacylglycerol/protein kinase C (DAG/PKC)... -
Federal
Insertion of a small peptide of six amino acids into the β7–β8 loop of the p51 subunit of HIV-1 reverse transcriptase perturbs the heterodimer and affects its activities
U.S. Department of Health & Human Services —
Background HIV-1 RT is a heterodimeric enzyme, comprising of the p66 and p51 subunits. Earlier, we have shown that the β7-β8 loop of p51 is a key structural element... -
Federal
The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity
U.S. Department of Health & Human Services —
Cytokines play a critical role in regulating lymphoid cell responses to most antigenic stimuli, and it is therefore very likely that these molecules profoundly affect... -
Federal
Research Article: BMC Medical Genetics
U.S. Department of Health & Human Services —
Background Narcolepsy is a common neuropsychiatric disorder characterized by increased daytime sleepiness, cataplexy and hypnagogic hallucinations. Deficiency of the... -
Federal
Protection against ultraviolet radiation by commercial summer clothing: need for standardised testing and labelling
U.S. Department of Health & Human Services —
Background The use of clothing as a means of sun protection has been recommended in recent education campaigns. Contrary to popular opinion, however, some fabrics... -
Federal
Two novel frame shift, recurrent and
U.S. Department of Health & Human Services —
We have identified four different mutations causing leukocyte adhesion deficiency (LAD) in the ITGB2 gene of patients from a highly inbred population. Two were novel... -
Federal
Decreases in blood perfusion of the anterior cingulate gyri in Anorexia Nervosa Restricters assessed by SPECT image analysis
U.S. Department of Health & Human Services —
Background It is possible that psychopathological differences exist between the restricting and bulimic forms of anorexia nervosa. We investigated localized... -
Federal
Lack of agreement between bioimpedance and continuous thermodilution measurement of cardiac output in intensive care unit patients
U.S. Department of Health & Human Services —
Background: Bolus thermodilution is the standard bedside method of cardiac output measurement in the intensive care unit (ICU). The Baxter Vigilance monitor uses a... -
Federal
Carbamazepine reduces memory induced activation of mesial temporal lobe structures: a pharmacological fMRI-study
U.S. Department of Health & Human Services —
Background and Purpose It is not known whether carbamazepine (CBZ; a drug widely used in neurology and psychiatry) influences the blood oxygenation level dependent... -
Federal
Lipoprotein profile in older patients with vascular dementia and Alzheimer's disease
U.S. Department of Health & Human Services —
Background Some alterations of the lipoprotein profile have been associated with cerebrovascular disease. Recently, it has been suggested that cerebrovascular disease...