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Federal
The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases
U.S. Department of Health & Human Services —
Background: Protein fold recognition using sequence profile searches frequently allows prediction of the structure and biochemical mechanisms of proteins with an... -
Federal
NEAT: a domain duplicated in genes near the components of a putative Fe
U.S. Department of Health & Human Services —
Iron uptake from the host is essential for bacteria that infect animals. A protein domain has been identified that appears in variable copy number in bacterial genes... -
Federal
Food intakes and preferences of hospitalised geriatric patients
U.S. Department of Health & Human Services —
Background A cross sectional survey was carried out on 120 hospitalised geriatric patients aged 60 and above in Hospital Universiti Kebangsaan Malaysia, Kuala Lumpur... -
Federal
An international survey of patients with thalassemia major and their views about sustaining life-long desferrioxamine use
U.S. Department of Health & Human Services —
Background Management of thalassemia major requires patients to have life-long access to a treatment regimen of regular blood transfusions coupled with iron chelation... -
Federal
Adaptations to iron deficiency: cardiac functional responsiveness to norepinephrine, arterial remodeling, and the effect of beta-blockade on cardiac hypertrophy
U.S. Department of Health & Human Services —
Background Iron deficiency (ID) results in ventricular hypertrophy, believed to involve sympathetic stimulation. We hypothesized that with ID 1) intravenous... -
Federal
Monoclonal antibodies against the iron regulated outer membrane Proteins of
U.S. Department of Health & Human Services —
Background Iron is an important nutrient required by all forms of life.In the case of human hosts,the free iron availability is 10-18M,which is far less than what is... -
Federal
A prospective, cross-sectional study of anaemia and peripheral iron status in antiretroviral naïve, HIV-1 infected children in Cape Town, South Africa
U.S. Department of Health & Human Services —
Background Anaemia is a common manifestation of paediatric HIV infection. Although there are many causes, anaemia of chronic diseases is the most frequent type. In... -
Federal
Survey of human mitochondrial diseases using new genomic/proteomic tools
U.S. Department of Health & Human Services —
Background We have constructed Bayesian prior-based, amino-acid sequence profiles for the complete yeast mitochondrial proteome and used them to develop methods for... -
Federal
Bacterial response to siderophore and quorum-sensing chemical signals in the seawater microbial community
U.S. Department of Health & Human Services —
Background Oceans are iron-deficient and nutrient-poor environments. These conditions impart limitations on our understanding of and our ability to identify... -
Federal
Desferrioxamine decreases NAD redox potential of intact red blood cells: evidence for desferrioxamine as an inducer of oxidant stress in red blood cells
U.S. Department of Health & Human Services —
Background Desferrioxamine (DFO) is an important iron chelating agent. It has also been thought of as an agent with anti-oxidant potential as it chelates ferric iron... -
Federal
Factors regulating Hb F synthesis in thalassemic diseases
U.S. Department of Health & Human Services —
Background The thalassemic syndromes originate from mutations of the globin genes that cause, besides the characteristic clinical picture, also an increased Hb F... -
Federal
Low molecular mass dinitrosyl nonheme-iron complexes up-regulate noradrenaline release in the rat tail artery
U.S. Department of Health & Human Services —
Background Dinitrosyl nonheme-iron complexes can appear in cells and tissues overproducing nitric oxide. It is believed that due to their chemical nature these... -
Federal
Structural, functional, and evolutionary analysis of
U.S. Department of Health & Human Services —
Background Pyridine-2,6-bis(thiocarboxylic acid) (pdtc) is a small secreted metabolite that has a high affinity for transition metals, increases iron uptake...