-
Federal
Oral contraceptive use before first birth and risk of breast cancer: a case control study
U.S. Department of Health & Human Services —
Background The aim of this study was first, to investigate whether women starting oral contraceptive (OC) use at a young age and before first birth have an increased... -
Federal
Ventilator-associated pneumonia in a surgical intensive care unit: epidemiology, etiology and comparison of three bronchoscopic methods for microbiological specimen sampling
U.S. Department of Health & Human Services —
Background: Ventilator-associated bacterial pneumonia (VAP) is a important intensive care unit (ICU)-acquired infection in mechanically ventilated patients. Early and... -
Federal
Treatment of established postoperative nausea and vomiting: a quantitative systematic review
U.S. Department of Health & Human Services —
Background The relative efficacy of antiemetics for the treatment of postoperative nausea and vomiting (PONV) is poorly understood. Methods Systematic search... -
Federal
The baboon (
U.S. Department of Health & Human Services —
Background As novel endovascular strategies are developed for treating neurological disease, there is an increasing need to evaluate these techniques in relevant... -
Federal
Mechanisms of bone loss in inflammatory arthritis: diagnosis and therapeutic implications
U.S. Department of Health & Human Services —
Rheumatoid arthritis represents an excellent model in which to gain insights into the local and systemic effects of joint inflammation on skeletal tissues. Three... -
Federal
Signal analysis of behavioral and molecular cycles
U.S. Department of Health & Human Services —
Background Circadian clocks are biological oscillators that regulate molecular, physiological, and behavioral rhythms in a wide variety of organisms. While behavioral... -
Federal
Are proton pump inhibitors the first choice for acute treatment of gastric ulcers? A meta analysis of randomized clinical trials
U.S. Department of Health & Human Services —
Background Gastric ulcers are a frequent problem in the United States. Proton pump inhibitors have been shown to increase healing rates and improve clinical symptoms.... -
Federal
How well can blood pressure be controlled? Progress report on the Systolic Hypertension in Europe Follow-Up Study (Syst-Eur 2)
U.S. Department of Health & Human Services —
Background The randomised, double-blind, placebo-controlled Systolic Hypertension in Europe trial (Syst-Eur 1) proved that blood pressure (BP) lowering therapy... -
Federal
Debate: A subversive view of subsets - a dissident clinician's opinion
U.S. Department of Health & Human Services —
Clinical trialists and statisticians are very wary of subgroup analysis, for good reasons. Clinicians have to deal with situations in which subgroups of patients... -
Federal
Human members of the eukaryotic protein kinase family
U.S. Department of Health & Human Services —
Publicly available genetic sequence data were searched for human sequences that potentially represent protein kinases, important players in virtually every signaling... -
Federal
Blood substitutes Artificial oxygen carriers: perfluorocarbon emulsions
U.S. Department of Health & Human Services —
Perfluorocarbon emulsions are being clinically evaluated as artificial oxygen carriers to reduce allogeneic blood transfusions or to improve tissue oxygenation.... -
Federal
Case-oriented computer-based-training in radiology: concept, implementation and evaluation
U.S. Department of Health & Human Services —
Background Providing high-quality clinical cases is important for teaching radiology. We developed, implemented and evaluated a program for a university hospital to... -
Federal
Policy mapping for establishing a national emergency health policy for Nigeria
U.S. Department of Health & Human Services —
Background The number of potential life years lost due to accidents and injuries though poorly studied has resulted in tremendous economic and social loss to Nigeria.... -
Federal
Insertion of a small peptide of six amino acids into the β7–β8 loop of the p51 subunit of HIV-1 reverse transcriptase perturbs the heterodimer and affects its activities
U.S. Department of Health & Human Services —
Background HIV-1 RT is a heterodimeric enzyme, comprising of the p66 and p51 subunits. Earlier, we have shown that the β7-β8 loop of p51 is a key structural element... -
Federal
Continuous haemofiltration in the intensive care unit
U.S. Department of Health & Human Services —
Continuous renal replacement therapy (CRRT) was first described in 1977 for the treatment of diuretic-unresponsive fluid overload in the intensive care unit (ICU).... -
Federal
Specificity of T cells in synovial fluid: high frequencies of CD8
U.S. Department of Health & Human Services —
CD8+ T cells dominate the lymphocyte population in synovial fluid in chronic inflammatory arthritis. It is known that these CD8+ T cells are often clonally or... -
Federal
Prevalence of hepatitis B and C markers in high-risk hospitalised patients in Crete: a five-year observational study
U.S. Department of Health & Human Services —
Background So far the prevalence of viral hepatitis infection in hospitalized patients has not been extensively studied. Therefore we conducted the present five-year... -
Federal
On the species of origin: diagnosing the source of symbiotic transcripts
U.S. Department of Health & Human Services —
Background Most organisms have developed ways to recognize and interact with other species. Symbiotic interactions range from pathogenic to mutualistic. Some... -
Federal
TheTnfrh1(Tnfrsf23) gene is weakly imprinted in several organs and expressed at the trophoblast-decidua interface
U.S. Department of Health & Human Services —
TheTnfrh1gene (gene symbolTnfrsf23) is located near one end of a megabase-scale imprinted region on mouse distal chromosome 7, about 350 kb distant from the nearest... -
Federal
Sex differences in risk factors for coronary heart disease: a study in a Brazilian population
U.S. Department of Health & Human Services —
Background In Brazil coronary heart disease (CHD) constitutes the most important cause of death in both sexes in all the regions of the country and interestingly, the...