-
Federal
Obstructive sleep apnea and vascular disease
U.S. Department of Health & Human Services —
There is emerging evidence linking obstructive sleep apnea (OSA) to vascular disease, including hypertension. This relationship may be independent of co-morbidity,... -
Federal
Diagnostic and treatment characteristics of polycystic ovary syndrome: descriptive measurements of patient perception and awareness from 657 confidential self-reports
U.S. Department of Health & Human Services —
Background This investigation was undertaken to describe patient perception and awareness of the polycystic ovary syndrome (PCOS), the most common cause of... -
Federal
A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database: design and methodology
U.S. Department of Health & Human Services —
Background An association between mumps-measles-rubella (MMR) vaccination and the onset of symptoms typical of autism has recently been suggested. This has led to... -
Federal
Representation of women's health in general medical versus women's health specialty journals: a content analysis
U.S. Department of Health & Human Services —
Background Women's health, traditionally defined, emphasises reproductive and maternal conditions without consideration of social contexts. Advocates urge a broader... -
Federal
Critical advances in septicemia and septic shock
U.S. Department of Health & Human Services —
Recent advances suggest that toll-like receptors, various cytokines, cicosanoids, free radicals and macrophage migration inhibitory factor (MIF) play an important... -
Federal
Risk factors for hospitalization among adults with asthma: the influence of sociodemographic factors and asthma severity
U.S. Department of Health & Human Services —
Background The morbidity and mortality from asthma have markedly increased since the late 1970s. The hospitalization rate, an important marker of asthma severity,... -
Federal
Human members of the eukaryotic protein kinase family
U.S. Department of Health & Human Services —
Publicly available genetic sequence data were searched for human sequences that potentially represent protein kinases, important players in virtually every signaling... -
Federal
Quantitative analysis of DNA levels in maternal plasma in normal and Down syndrome pregnancies
U.S. Department of Health & Human Services —
Background We investigated fetal and total DNA levels in maternal plasma in patients bearing fetuses affected with Down syndrome in comparison to controls carrying... -
Federal
Diagnostic criteria for diabetes revisited: making use of combined criteria
U.S. Department of Health & Human Services —
Background Existing cut-offs for fasting plasma glucose (FPG) and post-load glucose (2hPG) criteria are not equivalent in the diagnosis of diabetes and glucose... -
Federal
Case-oriented computer-based-training in radiology: concept, implementation and evaluation
U.S. Department of Health & Human Services —
Background Providing high-quality clinical cases is important for teaching radiology. We developed, implemented and evaluated a program for a university hospital to... -
Federal
In what extent anemia coexists with cognitive impairment in elderly: a cross-sectional study in Greece
U.S. Department of Health & Human Services —
Background A project aimed at studying the frequency of dementia and depression in the catchment area of the Health Centre of Chrissoupolis (HCCh), Northern Greece,... -
Federal
Design and performance of a multi-centre randomised controlled trial and economic evaluation of joint tele-consultations [ISRCTN54264250]
U.S. Department of Health & Human Services —
Background Appropriate information flow is crucial to the care of patients, particularly at the interface between primary and secondary care. Communication problems... -
Federal
Traumatic brain injury as a risk factor for Alzheimer disease. Comparison of two retrospective autopsy cohorts with evaluation of ApoE genotype
U.S. Department of Health & Human Services —
Background and Purpose The impact of traumatic brain injury (TBI) on the pathogenesis of Alzheimer disease (AD) is still controversial. The aim of our retrospective... -
Federal
Prescribing patterns in premenstrual syndrome
U.S. Department of Health & Human Services —
Background Over 300 therapies have been proposed for premenstrual syndrome. To date there has been only one survey conducted in the UK of PMS treatments prescribed by... -
Federal
Retrovirus-delivered siRNA
U.S. Department of Health & Human Services —
The ability of transfected synthetic small interfering (si) RNAs to suppress the expression of specific transcripts has proved a useful technique to probe gene... -
Federal
Little qualitative RNA misexpression in sterile male F
U.S. Department of Health & Human Services —
Background Although the genetics of hybrid sterility has been the subject of evolutionary studies for over sixty years, no one has shown the reason(s) why alleles... -
Federal
Phospholipase Cδ regulates germination of
U.S. Department of Health & Human Services —
Background Many eukaryotes, including plants and fungi make spores that resist severe environmental stress. The micro-organism Dictyostelium contains a single... -
Federal
Expression of monolysocardiolipin acyltransferase activity is regulated in concert with the level of cardiolipin and cardiolipin biosynthesis in the mammalian heart
U.S. Department of Health & Human Services —
Background Monolysocardiolipin acyltransferase (MLCL AT) catalyzes the acylation of monolysocardiolipin to cardiolipin in mammalian tissues. We previously reported... -
Federal
The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases
U.S. Department of Health & Human Services —
Background: Protein fold recognition using sequence profile searches frequently allows prediction of the structure and biochemical mechanisms of proteins with an... -
Federal
Debate: The slippery slope of surrogate outcomes
U.S. Department of Health & Human Services —
Surrogate outcomes are frequently used in cardiovascular disease research. A concern is that changes in surrogate markers may not reflect changes in disease outcomes....