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Federal
Bone loss: Epidemiology of bone loss
U.S. Department of Health & Human Services —
Bone loss occurs when the cellular events of bone formation are quantitatively larger than bone formation. This manuscript discusses the measurement of bone loss,... -
Federal
Design and implementation of microarray gene expression markup language (MAGE-ML)
U.S. Department of Health & Human Services —
Meaningful exchange of microarray data is currently difficult because it is rare that published data provide sufficient information depth or are even in the same... -
Federal
Correlation of the score for subjective pain with physical disability, clinical and radiographic scores in recent onset rheumatoid arthritis
U.S. Department of Health & Human Services —
Background To analyse the relationship between subjective pain score and other measures of clinical, radiographic and functional status; in particular Larsen... -
Federal
Open tension free repair of inguinal hernias; the Lichtenstein technique
U.S. Department of Health & Human Services —
Background Recurrences have been a significant problem following hernia repair. Prosthetic materials have been increasingly used in hernia repair to prevent... -
Federal
What kind of evidence is it that Evidence-Based Medicine advocates want health care providers and consumers to pay attention to?
U.S. Department of Health & Human Services —
Background In 1992, Evidence-Based Medicine advocates proclaimed a "new paradigm", in which evidence from health care research is the best basis for decisions for... -
Federal
The use of alternative therapies in the Saskatchewan stroke rehabilitation population
U.S. Department of Health & Human Services —
Background Many patients use alternative therapies. The purpose of this study was to determine the percentage of stroke rehabilitation patients in Saskatchewan using... -
Federal
T-cell-mediated control of autoimmunity
U.S. Department of Health & Human Services —
Inflammatory responses provoked by pathogens are antigen-specific in their induction but are nonspecific in their effects. Consequently, they are potentially damaging... -
Federal
Appetite suppressants and valvular heart disease – a systematic review
U.S. Department of Health & Human Services —
Background Although appetite suppressants have been implicated in the development of valvular heart disease, the exact level of risk is still uncertain. Initial... -
Federal
Why the fair innings argument is not persuasive
U.S. Department of Health & Human Services —
The fair innings argument (FIA) is frequently put forward as a justification for denying elderly patients treatment when they are in competition with younger patients... -
Federal
LDL-cholesterol lowering effect of a generic product of simvastatin compared to simvastatin (Zocor™) in Thai hypercholesterolemic subjects – a randomized crossover study, the first report from Thailand
U.S. Department of Health & Human Services —
Background It is commonly agreed that people with a high blood LDL-cholesterol will have a higher risk of coronary artery disease (CAD) than people with low blood... -
Federal
The significance of opthalmologic evaluation in the early diagnosis of inborn errors of metabolism: the Cretan experience
U.S. Department of Health & Human Services —
Background The Inborn Errors of Metabolism (IEM) are far from the rare systemic diseases that mainly affect the neural tissue. There are very few written reports on... -
Federal
Crystal structure of LIR-2 (ILT4) at 1.8 Å: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18
U.S. Department of Health & Human Services —
Background Leukocyte Immunoglobulin-like Receptor-1 (LIR-1) and LIR-2 (also known as ILT2 and ILT4 respectively) are highly related cell surface receptors that bind a... -
Federal
The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells
U.S. Department of Health & Human Services —
Background The cyclin-dependent kinase inhibitor p27 is a putative tumor suppressor that is downregulated in the majority of human prostate cancers. The mechanism of... -
Federal
GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors
U.S. Department of Health & Human Services —
Background Based on sequence similarity, the superfamily of G protein-coupled receptors (GPRs) can be subdivided into several subfamilies, the members of which often... -
Federal
Analysis of fluorescently labeled substance P analogs: binding, imaging and receptor activation
U.S. Department of Health & Human Services —
Background Substance P (SP) is a peptide neurotransmitter found in central and peripheral nerves. SP is involved in the control of smooth muscle, inflammation and... -
Federal
SNP frequency, haplotype structure and linkage disequilibrium in elite maize inbred lines
U.S. Department of Health & Human Services —
Background Recent studies of ancestral maize populations indicate that linkage disequilibrium tends to dissipate rapidly, sometimes within 100 bp. We set out to... -
Federal
General Practitioners' views on the provision of nicotine replacement therapy and bupropion
U.S. Department of Health & Human Services —
Background Nicotine replacement therapies (NRT) and a new drug, bupropion, are licensed in several countries as aids to smoking cessation. General practitioners (GPs)... -
Federal
Systematic review of the use of honey as a wound dressing
U.S. Department of Health & Human Services —
Objective To investigate topical honey in superficial burns and wounds though a systematic review of randomised controlled trials. Data sources Cochrane Library,... -
Federal
Influence of CSP 310 and CSP 310-like proteins from cereals on mitochondrial energetic activity and lipid peroxidation
U.S. Department of Health & Human Services —
Background The development of chilling and freezing injury symptoms in plants is known to frequently coincide with peroxidation of free fatty acids. Mitochondria are... -
Federal
Which treatment for low back pain? A factorial randomised controlled trial comparing intravenous analgesics with oral analgesics in the emergency department and a centrally acting muscle relaxant with placebo over three days [ISRCTN09719705]
U.S. Department of Health & Human Services —
Background About two thirds of adults suffer from backpain at some time during their life. In the emergency room many patients with acute back pain are treated with...