66 datasets found
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Federal
A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics
U.S. Environmental Protection Agency —
The U.S. Tox21 Federal collaboration, which currently quantifies the biological effects of nearly 10,000 chemicals via quantitative high-throughput screening(qHTS) in... -
Federal
CHEMICAL CHARACTERIZATION OF RECYCLED CONSUMER PRODUCTS USING SUSPECT SCREENING ANALYSIS
U.S. Environmental Protection Agency —
All data associated with Figures and Tables of manuscript "CHEMICAL CHARACTERIZATION OF RECYCLED CONSUMER PRODUCTS USING SUSPECT SCREENING ANALYSIS", Charles Lowe et... -
Federal
In vivo plasma concentration for lindane after 6 hour exposure in human skin
U.S. Environmental Protection Agency —
Dataset is a time course description of lindane disappearance in blood plasma after dermal exposure in human volunteers. This dataset is associated with the following... -
Federal
Characterizing Chemical Exposure Trends from NHANES Urinary Biomonitoring Data
U.S. Environmental Protection Agency —
Supplementary material for "Characterizing Chemical Exposure Trends from NHANES Urinary Biomonitoring Data". This dataset is associated with the following... -
Federal
Quantitative Structure-Use Relationship Model Predictions to evaluate Tox21 Chemicals as Functional Substitutes and Candidate Alternatives
U.S. Environmental Protection Agency —
This dataset provides a prediction for all Tox21 chemicals with available QSUR descriptors across all 41 valid QSUR models developed with FUse. This dataset is... -
Federal
Development and Evaluation of a High Throughput Inhalation Model for Organic Chemicals
U.S. Environmental Protection Agency —
This investigation was broken down into three interrelated steps: data collection, model building, and model evaluation. R software (v. 3.5.1) with the httk package... -
Federal
CES_EHP_Figure_2
U.S. Environmental Protection Agency —
The increasing number of chemicals for which SHEDS probabilistic exposure assessment has been performed over the years. This dataset is associated with the following... -
Federal
(Archives of Toxicology) Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment
U.S. Environmental Protection Agency —
To determine the best way to select predictive groups of genes, we used published microarray data from dose-response studies on six chemicals in rats exposed orally... -
Federal
(REPRODUCTIVE TOXICOLOGY) EMBRYONIC VASCULAR DISRUPTION ADVERSE OUTCOMES: LINKING HIGH THROUGHPUT SIGNALING SIGNATURES WITH FUNCTIONAL CONSEQUENCES
U.S. Environmental Protection Agency —
This study evaluated two anti-angiogenic agents, 5HPP-33 and TNP-470, across the ToxCastDB HTS assay platform and anchored the results to complex in vitro functional... -
Federal
Datasets associated with "Mining of Consumer Product and Purchasing Data to Identify Potential Chemical Co-exposures"
U.S. Environmental Protection Agency —
Background: Chemicals in consumer products are a major contributor to human chemical co-exposures. Consumers purchase and use a wide variety of products containing... -
Federal
A geospatial modeling approach to quantifying the risk of exposure to environmental chemical mixtures via a common molecular target
U.S. Environmental Protection Agency —
Data files for "Eccles KM, Karmaus AL, Kleinstreuer NC, Parham F, Rider CV, Wambaugh JF, Messier KP. A geospatial modeling approach to quantifying the risk of... -
Federal
HTTK R Package v1.5 - Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability
U.S. Environmental Protection Agency —
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from... -
Federal
Datasets for PUC paper 09182018
U.S. Environmental Protection Agency —
Datasets associated with the publication "Establishing a System of Consumer Products Categories to Support Rapid Modeling of Human Exposure". This dataset is... -
Federal
(Crit. Rev. Tox.) Comparing rat and rabbit embryo-fetal developmental toxicity studies for 379 pharmaceuticals: On systemic dose and developmental effects
U.S. Environmental Protection Agency —
A database of embryo-fetal developmental toxicity (EFDT) studies of 379 pharmaceutical compounds in rat and rabbit. This dataset is not publicly accessible because:... -
Federal
ORD-017311_Data_Brown_DermPerm.xlsx
U.S. Environmental Protection Agency —
List of chemicals used for model evaluation, their MW, log KOW, and references for the original data source(s), the review(s) the data was collected from, and... -
Federal
The chemical landscape of high-throughput new approach methodologies for exposure
U.S. Environmental Protection Agency —
Data for the publication Isaacs, K.K., Egeghy, P., Dionisio, K.L. et al. The chemical landscape of high-throughput new approach methodologies for exposure. J Expo Sci... -
Federal
Non‐animal assessment of skin sensitization hazard: Is an integrated testing strategy needed, and if so what should be integrated?
U.S. Environmental Protection Agency —
Appendix Skin sensitization data and non‐animal test data for 271 chemicals. This dataset is associated with the following publication: Roberts, D., and G. Patlewicz.... -
Federal
High-Throughput Dietary Exposure Predictions for Chemical Migrants from Food Contact Substances for Use in Chemical Prioritization
U.S. Environmental Protection Agency —
Under the ExpoCast program, United States Environmental Protection Agency (EPA) researchers have developed a high-throughput (HT) framework for estimating aggregate... -
Federal
Development of a Flame Retardant and an Organohalogen Flame Retardant Chemical Inventory
U.S. Environmental Protection Agency —
This dataset is the result of a joint EPA-CPSC effort to catalogue flame retardant (and more specifically organohalogen flame retardant chemicals). Full details of... -
Federal
Weaver's historic accessible collection of synthetic dyes: a cheminformatics analysis
U.S. Environmental Protection Agency —
This is a subset of 150 chemical dyes that are housed in the Max Weaver Dye Library at North Carolina State University HISTORY. This dataset is associated with the...
66 datasets found