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Federal
Risk of mortality in a cohort of patients newly diagnosed with chronic atrial fibrillation
U.S. Department of Health & Human Services —
Objective To estimate the mortality rate of patients newly diagnosed with chronic atrial fibrillation (AF) and compare it with the one in the general population. To... -
Federal
Skeletal muscle dysfunction in chronic obstructive pulmonary disease
U.S. Department of Health & Human Services —
It has become increasingly recognized that skeletal muscle dysfunction is common in patients with chronic obstructive pulmonary disease (COPD). Muscle strength and... -
Federal
Apolipoprotein E gene polymorphism is not a strong risk factor for diabetic nephropathy and retinopathy in Type I diabetes: case-control study
U.S. Department of Health & Human Services —
Background The gene encoding apolipoprotein E (APOE) has been proposed as a candidate gene for vascular complications in Type I diabetes. This study aimed to... -
Federal
A surrogate-based approach for post-genomic partner identification
U.S. Department of Health & Human Services —
Background Modern drug discovery is concerned with identification and validation of novel protein targets from among the 30,000 genes or more postulated to be present... -
Federal
Vasopressin-dependent flank marking in golden hamsters is suppressed by drugs used in the treatment of obsessive-compulsive disorder
U.S. Department of Health & Human Services —
Background Alterations in arginine vasopressin regulation and secretion have been proposed as one possible biochemical abnormality in patients with obsessive-... -
Federal
Prediction of co-regulated genes in
U.S. Department of Health & Human Services —
Background Identification of co-regulated genes is essential for elucidating transcriptional regulatory networks and the function of uncharacterized genes. Although... -
Federal
Influence of twenty-five per cent human serum albumin on total and ionized calcium concentrations
U.S. Department of Health & Human Services —
Background: A inverse correlation has been found between changes in ionized calcium concentrations and the addition of albumin in vitro, which may explain adverse... -
Federal
Abnormal expression of p27kip1 protein in levator ani muscle of aging women with pelvic floor disorders – a relationship to the cellular differentiation and degeneration
U.S. Department of Health & Human Services —
Background Pelvic floor disorders affect almost 50% of aging women. An important role in the pelvic floor support belongs to the levator ani muscle. The p27/kip1... -
Federal
Prescribing patterns in premenstrual syndrome
U.S. Department of Health & Human Services —
Background Over 300 therapies have been proposed for premenstrual syndrome. To date there has been only one survey conducted in the UK of PMS treatments prescribed by... -
Federal
The attributable mortality and length of intensive care unit stay of clinically important gastrointestinal bleeding in critically ill patients
U.S. Department of Health & Human Services —
Objective To estimate the mortality and length of stay in the intensive care unit (ICU) attributable to clinically important gastrointestinal bleeding in mechanically... -
Federal
Alarms in the intensive care unit: how can the number of false alarms be reduced?
U.S. Department of Health & Human Services —
Many alarms, as they now exist in most monitoring systems, are not usually perceived as helpful by the medical staff because of the high incidence of false alarms.... -
Federal
Effects of microcosm scaling and food resources on growth and survival of larval
U.S. Department of Health & Human Services —
Background We used a simple experimental design to test for the effects of microcosm scaling on the growth and survival of the mosquito, Culex pipiens. Microcosm and... -
Federal
Treatment of established postoperative nausea and vomiting: a quantitative systematic review
U.S. Department of Health & Human Services —
Background The relative efficacy of antiemetics for the treatment of postoperative nausea and vomiting (PONV) is poorly understood. Methods Systematic search... -
Federal
Evaluation of thresholds for the detection of binding sites for regulatory proteins in
U.S. Department of Health & Human Services —
Background Sites in DNA that bind regulatory proteins can be detected computationally in various ways. Pattern discovery methods analyze collections of genes... -
Federal
The methionine salvage pathway in
U.S. Department of Health & Human Services —
Background Polyamine synthesis produces methylthioadenosine, which has to be disposed of. The cell recycles it into methionine through methylthioribose (MTR). Very... -
Federal
B lymphocyte involvement in ankylosing spondylitis: the heavy chain variable segment gene repertoire of B lymphocytes from germinal center-like foci in the synovial membrane indicates antigen selection
U.S. Department of Health & Human Services —
The synovial membrane (SM) of affected joints in ankylosing spondylitis (AS) is infiltrated by germinal center-like aggregates (foci) of lymphocytes similar to... -
Federal
Separate urinary bladder and prostate neurons in the central nervous system of the rat: simultaneous labeling with two immunohistochemically distinguishable pseudorabies viruses
U.S. Department of Health & Human Services —
Background This work examines the central nervous system distribution of virus-labeled neurons from the rat urinary bladder and the prostate simultaneously within the... -
Federal
Do we need clinical trials to test the ability of transdermal HRT to prevent coronary heart disease?
U.S. Department of Health & Human Services —
Postmenopausal hormone replacement therapy (HRT) with oral oestrogen was predicted to reduce coronary heart disease (CHD) risk by 50%. Randomized controlled trials... -
Federal
Longitudinal impact of a youth tobacco education program
U.S. Department of Health & Human Services —
Background Information on the effectiveness of elementary school level, tobacco-use prevention programs is generally limited. This study assessed the impact of a... -
Federal
Effects of herbivory on the reproductive effort of 4 prairie perennials
U.S. Department of Health & Human Services —
Background Herbivory can affect every aspect of a plant's life. Damaged individuals may show decreased survivorship and reproductive output. Additionally, specific...