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Federal
Hamster oocyte membrane potential and ion permeability vary with preantral cumulus cell attachment and developmental stage
U.S. Department of Health & Human Services —
Background In vitro maturation of mammalian oocytes is an area of great interest due to its potential application in the treatment of infertility. The morphological... -
Federal
Survey of stress ulcer prophylaxis
U.S. Department of Health & Human Services —
Background: No surveys of stress ulcer prophylaxis prescribing in the USA have been conducted since 1995. Since that time, the most comprehensive meta-analysis and... -
Federal
Both subtelomeric regions are required and sufficient for specific DNA fragmentation during macronuclear development in
U.S. Department of Health & Human Services —
Background: Programmed DNA-reorganization and DNA-elimination events take place frequently during cellular differentiation. An extreme form of such processes,... -
Federal
Conservation and diversity of gene families explored using the CODEHOP strategy in higher plants
U.S. Department of Health & Human Services —
Background Availability of genomewide information on an increasing but still limited number of plants offers the possibility of identifying orthologues, or related... -
Federal
New approaches to the modulation of inflammatory processes in airway disease models: ATS 2001, May 18-23, San Francisco
U.S. Department of Health & Human Services —
The 97th American Thoracic Society meeting proved to be an excellent meeting, providing a wealth of new information on inflammatory diseases of the airways. Once... -
Federal
Mobilization of seed storage lipid by Arabidopsis seedlings is retarded in the presence of exogenous sugars
U.S. Department of Health & Human Services —
Background Soluble sugar levels must be closely regulated in germinating seeds to ensure an adequate supply of energy and building materials for the developing... -
Federal
Microarray profile of differentially expressed genes in a monkey model of allergic asthma
U.S. Department of Health & Human Services —
Background Inhalation of Ascaris suum antigen by allergic monkeys causes an immediate bronchoconstriction and delayed allergic reaction, including a pulmonary... -
Federal
Biomechanical evaluation of immediate stability with rectangular versus cylindrical interbody cages in stabilization of the lumbar spine
U.S. Department of Health & Human Services —
Background Recent cadaver studies show stability against axial rotation with a cylindrical cage is marginally superior to a rectangular cage. The purpose of this... -
Federal
First isolation of the enterohaemorrhagic
U.S. Department of Health & Human Services —
Background Enterohaemorrhagic Escherichia coli (EHEC) is considered to be common cause of haemorrhagic colitis (HC), thrombotic thrombocytopenic purpura and... -
Federal
Cathepsin B cleavage of the trypsinogen activation peptide
U.S. Department of Health & Human Services —
Background Cathepsin B is thought to play a central role in intrapancreatic trypsinogen activation and the onset of pancreatitis. A recent investigation of the... -
Federal
Research Article: BMC Pharmacology
U.S. Department of Health & Human Services —
Background Leishmaniasis is a common parasitic disease in Southern Europe, caused by Leishmania infantum. The failures of current treatment with pentavalent... -
Federal
Reinforcement of genetic coherence in a two-locus model
U.S. Department of Health & Human Services —
Background In order to maintain populations as units of reproduction and thus enable anagenetic evolution, genetic factors must exist which prevent continuing... -
Federal
Modulation of cathepsin G expression in severe atopic dermatitis following medium-dose UVA1 phototherapy
U.S. Department of Health & Human Services —
Background During the last decade, medium-dose UVA1 phototherapy (50 J/cm2) has achieved great value within the treatment of severe atopic dermatitis (AD). The... -
Federal
Subunit modification and association in VR1 ion channels
U.S. Department of Health & Human Services —
Background The capsaicin (vanilloid) receptor, VR1, is an agonist-activated ion channel expressed by sensory neurons that serves as a detector of chemical and thermal... -
Federal
Retroviral vectors for establishing tetracycline-regulated gene expression in an otherwise recalcitrant cell line
U.S. Department of Health & Human Services —
Background Tetracycline-regulated systems have been used to control the expression of heterologous genes in such diverse organisms as yeast, plants, flies and mice.... -
Federal
Sequence requirements for RNA strand transfer during nidovirus discontinuous subgenomic RNA synthesis
U.S. Department of Health & Human Services —
Nidovirus subgenomic mRNAs contain a leader sequence derived from the 5′ end of the genome fused to different sequences (‘bodies’) derived from the 3′ end. Their... -
Federal
Blood borne transit of CJD from brain to gut at early stages of infection
U.S. Department of Health & Human Services —
Background In Creutzfeldt-Jakob disease (CJD) and other related transmissible spongiform encephalopathies it is critical to understand the various pathways by which... -
Federal
Rational use of computerized protocols in the intensive care unit
U.S. Department of Health & Human Services —
Excess information in complex ICU environments exceeds human decision making limits, increasing the likelihood of clinical errors. Explicit decision-support tools... -
Federal
Expression of p53, inducible nitric oxide synthase and vascular endothelial growth factor in gastric precancerous and cancerous lesions: correlation with clinical features
U.S. Department of Health & Human Services —
Background The growth and metastasis of tumors depend on the development of an adequate blood supply via angiogenesis. Recent studies indicate that the inducible... -
Federal
Treatment of achalasia: the short-term response to botulinum toxin injection seems to be independent of any kind of pretreatment
U.S. Department of Health & Human Services —
Background It has been suggested that intrasphincteric injection of botulinum toxin (BTX) may represent an alternative therapy to balloon dilatation in achalasia. The...