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Federal
The (CTG)n polymorphism in the NOTCH4 gene is not associated with schizophrenia in Japanese individuals
U.S. Department of Health & Human Services —
Background The human NOTCH4 gene is a candidate gene for schizophrenia due to its chromosomal location and neurobiological roles. In a British linkage study, NOTCH4... -
Federal
Genetics of osteoarticular disorders, Florence, Italy, 22–23 February 2002
U.S. Department of Health & Human Services —
Osteoporosis (OP) and osteoarthritis (OA), the two most common age-related chronic disorders of articular joints and skeleton, represent a major public health problem... -
Federal
Survey of the knowledge, attitude and practice of Nigerian surgery trainees to HIV-infected persons and AIDS patients
U.S. Department of Health & Human Services —
Background The incidence of HIV infection and AIDS is rising in Nigeria. Surgeons are at risk of occupationally acquired infection as a result of intimate contact... -
Federal
A mathematical model of optimized radioiodine-131 therapy of Graves' hyperthyroidism
U.S. Department of Health & Human Services —
Background The current status of radioiodine-131 (RaI) dosimetry for Graves' hyperthyroidism is not clear. Recurrent hyperthyroidism and iatrogenic hypothyroidism are... -
Federal
Research Article: Breast Cancer Research
U.S. Department of Health & Human Services —
Background The contribution of BRCA1 and BRCA2 to the incidence of male breast cancer (MBC) in the United Kingdom is not known, and the importance of these genes in... -
Federal
Molecular action of methotrexate in inflammatory diseases
U.S. Department of Health & Human Services —
Despite the recent introduction of biological response modifiers and potent new small-molecule antirheumatic drugs, the efficacy of methotrexate is nearly unsurpassed... -
Federal
Modeling of failure mode in knee ligaments depending on the strain rate
U.S. Department of Health & Human Services —
Background The failure mechanism of the knee ligament (bone-ligament-bone complex) at different strain rates is an important subject in the biomechanics of the knee.... -
Federal
Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer
U.S. Department of Health & Human Services —
Background Drug resistance in breast cancer is a major obstacle to successful chemotherapy. In this study we used cDNA microarray technology to examine gene... -
Federal
The effectiveness of reducing the daily dose of finasteride in men with benign prostatic hyperplasia
U.S. Department of Health & Human Services —
Background Finasteride, a 5 alpha reductase inhibitor, is an established treatment for benign prostatic hyperplasia. The recommended dosage is 5 mg a day, however... -
Federal
Long-term reductions in tinnitus severity
U.S. Department of Health & Human Services —
Background This study was undertaken to assess long-term changes in tinnitus severity exhibited by patients who completed a comprehensive tinnitus management program;... -
Federal
Sex differences in risk factors for coronary heart disease: a study in a Brazilian population
U.S. Department of Health & Human Services —
Background In Brazil coronary heart disease (CHD) constitutes the most important cause of death in both sexes in all the regions of the country and interestingly, the... -
Federal
Safety of a new extensively hydrolysed formula in children with cow's milk protein allergy: a double blind crossover study
U.S. Department of Health & Human Services —
Background Formulae for infants with cow's milk protein allergy (CMA) should be based on extensively hydrolysed protein. 'Extensively' however is not strictly... -
Federal
Low frequency of
U.S. Department of Health & Human Services —
In order to explore the possible role of E-cadherin in familial cancer, 19 familial breast cancer patients, whose tumours demonstrated loss of heterozygosity (LOH) at... -
Federal
A successful pregnancy following SEM fine tuning of hormonal priming
U.S. Department of Health & Human Services —
Background Manipulation of the uterine epithelium utilising standard dose exogenous oestrogen (E2) and progesterone (P4) has been shown to achieve a mature secretory... -
Federal
Risk factors for breast cancer in Iran: a case-control study
U.S. Department of Health & Human Services —
Background Iranian breast cancer patients are relatively younger than their Western counterparts. The objective of the present study was to investigate risk factors... -
Federal
Prevalence of hepatitis B and C markers in high-risk hospitalised patients in Crete: a five-year observational study
U.S. Department of Health & Human Services —
Background So far the prevalence of viral hepatitis infection in hospitalized patients has not been extensively studied. Therefore we conducted the present five-year... -
Federal
A surrogate-based approach for post-genomic partner identification
U.S. Department of Health & Human Services —
Background Modern drug discovery is concerned with identification and validation of novel protein targets from among the 30,000 genes or more postulated to be present... -
Federal
Vasopressin-dependent flank marking in golden hamsters is suppressed by drugs used in the treatment of obsessive-compulsive disorder
U.S. Department of Health & Human Services —
Background Alterations in arginine vasopressin regulation and secretion have been proposed as one possible biochemical abnormality in patients with obsessive-... -
Federal
Influence of twenty-five per cent human serum albumin on total and ionized calcium concentrations
U.S. Department of Health & Human Services —
Background: A inverse correlation has been found between changes in ionized calcium concentrations and the addition of albumin in vitro, which may explain adverse... -
Federal
Prescribing patterns in premenstrual syndrome
U.S. Department of Health & Human Services —
Background Over 300 therapies have been proposed for premenstrual syndrome. To date there has been only one survey conducted in the UK of PMS treatments prescribed by...