288 datasets found
-
Federal
T Cell Activation in Microgravity Compared to 1g (Earth's) Gravity
National Aeronautics and Space Administration —
This study tested the hypothesis that transcription of immediate early genes is inhibited in T cells activated in microgravity (uG). Immunosuppression during... -
Federal
Metagenome profiling of feces from mice flown on the RRRM-1 mission
National Aeronautics and Space Administration —
In Rodent Research Reference Mission-1 (RRRM-1), forty female BALB/cAnNTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
Draft genome sequence of Klebsiella quasipneumoniae subsp. similipneumoniae strain IF3SW-P1 isolated from the International Space Station
National Aeronautics and Space Administration —
In 2015, the Advanced Resistive Exercise Device (ARED) foot panel on the International Space Station (ISS) was sampled to identify culturable microorganisms. The... -
Federal
Transcriptional profiling of mammary glands from mice flown on the RRRM-1 mission
National Aeronautics and Space Administration —
In Rodent Research Reference Mission-1 (RRRM-1), also known as RR-8, forty female BALB/cAnNTac mice were flown on the International Space Station. To assess... -
Federal
Integrative Transcriptomics and Proteomics Profiling of Arabidopsis thaliana Elucidates Novel Mechanisms Underlying Spaceflight Adaptation
National Aeronautics and Space Administration —
Spaceflight presents a unique environment with complex stressors, including microgravity and radiation, that can influence plant physiology at molecular levels.... -
Federal
Spaceflight effects on the mouse retina: Histological, gene expression and epigenetic changes after flight on STS-135
National Aeronautics and Space Administration —
We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing... -
Federal
Elevated plus-maze performance of Fischer-344 rats as a function of age and of exposure to 56Fe particles
National Aeronautics and Space Administration —
The aging process is characterized by a series of changes in neurochemical functioning and in motor and cognitive performance. In addition to changes in... -
Federal
Spaceflight-induced (STS-62) vertebral bone loss in ovariectomized rats is associated with increased bone marrow adiposity and no change in bone formation
National Aeronautics and Space Administration —
There is often a reciprocal relationship between bone marrow adipocytes and osteoblasts, suggesting that marrow adipose tissue (MAT) antagonizes osteoblast... -
Federal
STS-135 Liver Metabolomics
National Aeronautics and Space Administration —
Mice were flown onboard STS-135 and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples were... -
Federal
Delayed Cardiomyocyte Response to Total Body Particle Radiation Exposure - Identification of Regulatory Gene Network [iron]
National Aeronautics and Space Administration —
We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1... -
Federal
Biological Research in Canisters-16 (BRIC-16): Transcriptomics, Glycomics, and Morphometric photography.
National Aeronautics and Space Administration —
These investigations studied the fundamentals of how plants perceive gravity and develop in microgravity. It informs how gene regulation is altered by spaceflight... -
Federal
Transcriptional analysis of kidneys from mice flown on the RR-7 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-7 mission (RR-7) was to study the impact of the space environment on the gut microbiota of two strains of mice and how any... -
Federal
Draft Genomes of Fungi Isolated from the International Space Station during the Microbial Tracking-2 Experiment
National Aeronautics and Space Administration —
Draft genomes of fungi isolated from different surfaces on the International Space Station, as part of the Microbial Tracking 2 mission (ISS-MOP). -
Federal
Bulk RNA sequencing and single nuclei transcriptomics and epigenomics of brain tissue from mice flown on the RRRM-2 mission
National Aeronautics and Space Administration —
In the Rodent Research Reference Mission (RRRM-2), forty female C57BL/6NTac mice were flown on the International Space Station. To assess differences in outcomes due... -
Federal
Effects of low-dose oxygen ions and protons on cardiac function and structure in male C57BL/6J mice (echocardiogram/ultrasonography)
National Aeronautics and Space Administration —
Purpose: Astronauts traveling beyond low Earth orbit will be exposed to high linear energy transfer charged particles. Because there is concern about the adverse... -
Federal
Microbiological and nutritional analysis of lettuce crops grown on the International Space Station-VEG03A
National Aeronautics and Space Administration —
The ability to grow safe, fresh food to supplement packaged foods of astronauts in space has been an important goal for NASA. Food crops grown in space experience... -
Federal
Resequencing of select microbial isolates from the International Space Station with the Nanopore MinION
National Aeronautics and Space Administration —
Microbial isolates from the NASA Space Biology-funded microbial tracking experiments were re-sequenced using the Oxford Nanopore MinION. -
Federal
Fifteen days of microgravity causes growth in calvaria of mice (STS-131)
National Aeronautics and Space Administration —
Bone growth may occur in spaceflight as a response to skeletal unloading and head-ward fluid shifts. While unloading causes significant loss of bone mass and density... -
Federal
Characterization of mouse ocular responses (intraocular pressure) to a 35-day (RR-9) spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations
National Aeronautics and Space Administration —
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was... -
Federal
Characterization of mouse ocular responses (Microscopy) to a 35-day (RR-9) spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations
National Aeronautics and Space Administration —
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was...
288 datasets found