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Federal
Light has a principal role in the Arabidopsis transcriptomic response to the spaceflight environment
National Aeronautics and Space Administration —
The Characterizing Arabidopsis Root Attractions (CARA) spaceflight experiment provides comparative transcriptome analyses of plants grown in both light and dark... -
Federal
Transcriptional profiling of thymus from mice flown on the RR-9 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration... -
Federal
Quantitative evaluation of bioaerosols in different particle size fractions collected on the International Space Station (ISS)
National Aeronautics and Space Administration —
Exposure to bioaerosols can negatively impact human health. On the International Space Station (ISS) this exposure differs to that on Earth due to lack of... -
Federal
Root transcriptome remodeling of Arabidopsis in response to high levels of magnesium sulfate
National Aeronautics and Space Administration —
Martian regolith (unconsolidated surface material) is a potential medium for plant growth in bioregenerative life support systems during manned missions on Mars.... -
Federal
Gamma radiation and HZE treatment of seedlings in Arabidopsis
National Aeronautics and Space Administration —
Plants exhibit a robust transcriptional response to gamma radiation which includes the induction of transcripts required for homologous recombination and the... -
Federal
Effect of spaceflight on liver from mice flown on the ISS for 33 days: transcriptional analysis
National Aeronautics and Space Administration —
The objective of the Rodent Research-9 (RR-9) mission was to use mice to understand the molecular basis of phenomena that affect astronauts during long-duration... -
Federal
Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats (Femur - microCT, three-point bending, histomorphometry)
National Aeronautics and Space Administration —
Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of... -
Federal
Comparing RNA-Seq and microarray gene expression data in two zones of the Arabidopsis root apex relevant to spaceflight.
National Aeronautics and Space Administration —
Premise of the study: The root apex is an important region involved in environmental sensing, but comprises a very small part of the root. Obtaining root apex... -
Federal
Combined space stressors induce independent behavioral deficits predicted by early peripheral blood monocytes (Behavioral Assays)
National Aeronautics and Space Administration —
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to... -
Federal
Plant Gravity Perception (PGP) Flight Study
National Aeronautics and Space Administration —
This study investigated plant responses to a range of gravity treatments. Altered gravity was achieved by growing seedlings on the ISS within the centrifuge of the... -
Federal
Characterization of Biofilm Formation, Growth, and Gene Expression on Different Materials and Environmental Conditions in Microgravity (Morphology of Penicillium rubens biofilms)
National Aeronautics and Space Administration —
Microorganisms' natural ability to live as organized multicellular communities – also known as biofilms – provides them with unique survival advantages. For instance,... -
Federal
Transcription profiling by array of the response of Arabidopsis cultivar Columbia etiolated seedlings and undifferentiated tissue culture cells to the spaceflight environment
National Aeronautics and Space Administration —
We address a key baseline question of whether gene expression changes are induced by the orbital environment, and then we ask whether undifferentiated cells, cells... -
Federal
Transcriptional profiling of livers from mice flown on the RR-23 mission
National Aeronautics and Space Administration —
The objective of the RR-23 mission was to better understand the effects of spaceflight on the eyes, specifically on the structure and function of the arteries, veins,... -
Federal
Comparative Genomic Analysis of Klebsiella Exposed to Various Space Conditions at the International Space Station
National Aeronautics and Space Administration —
Due to the bacteria's evolved resistance to radiation, Klebsiella poses a great threat to not only planetary protection, but also to the integrity of future... -
Federal
Whole metagenome profiles of particulates collected from the International Space Station.
National Aeronautics and Space Administration —
The microbial composition of the International Space Station (ISS) environment is of critical interest due to potential impact of its constituents on human health and... -
Federal
Transcriptional profiling of colon from mice flown on the RR-10 mission
National Aeronautics and Space Administration —
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue... -
Federal
Transcription profiling of rat keratinocytes exposed to a 56Fe ion beam
National Aeronautics and Space Administration —
The purpose of the present work was to examine gene expression patterns in a rat keratinocyte line exposed to a 56Fe ion beam Experiment Overall Design: The cells... -
Federal
Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection
National Aeronautics and Space Administration —
To reveal outcomes of microgravity on molecular processes within the cellular environment we have employed a mass-spectrometry based proteomics approach. Proteomics... -
Federal
Effects of 32 Days Aboard the ISS on Gastrocnemius Tendon Nanomechanics (Gastrocnemius tendon, RR-1 and Atomic Force Microscopy)
National Aeronautics and Space Administration —
Collagen is an essential component of connective tissue and plays a crucial role in elasticity, stability, and force distribution. While the adaptations of tendon to... -
Federal
Transcriptional profiling of roots and shoots from Brachypodium distachyon seedlings flown on the ISS
National Aeronautics and Space Administration —
Most major cereal grain crops are monocots. Yet, most investigations of plant adaptation to the spaceflight environment have been carried out on the dicotyledonous...