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Federal
Exposure to elevated relative humidity in laboratory chambers alters fungal gene expression in dust from the International Space Station (ISS)
National Aeronautics and Space Administration —
Microbes are present in all occupied indoor environments, including the International Space Station (ISS). An unexpected ventilation system failure may lead to... -
Federal
The International Space Station Has a Unique and Extreme Microbial and Chemical Environment Driven by Use Patterns
National Aeronautics and Space Administration —
Space habitation provides unique challenges in built environments isolated from Earth. We produced a 3D map of the microbes and metabolites throughout the... -
Federal
Influence of gonadectomy on muscle health in micro- and partial-gravity environments in rats (Grip; force transducer)
National Aeronautics and Space Administration —
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle... -
Federal
Space environmental factor impacts upon murine colon microbiota and mucosal homeostasis
National Aeronautics and Space Administration —
We report how high and low linear energy transfer (LET) radiation, microgravity, and elevated dietary iron affect colon microbiota (determined by 16S rDNA... -
Federal
Gene expression profiling for spaceflight induced-neuroinflammation in the mouse brain
National Aeronautics and Space Administration —
The health risk from spaceflight-induced neuronal damage and potential adverse neurovascular effects is a chief concern. More recently, it has been proposed that... -
Federal
Effects of low dose space radiation exposures on the splenic metabolome
National Aeronautics and Space Administration —
Future space missions will include return to the Moon and long duration deep space roundtrip missions to Mars. Leaving the protection that Low Earth Orbit provides... -
Federal
Influence of gonadectomy on muscle health in micro- and partial-gravity environments in rats (Estrous Cycle Monitoring)
National Aeronautics and Space Administration —
Gonadal hormones, such as testosterone and estradiol, modulate muscle size and strength in males and females. However, the influence of sex hormones on muscle... -
Federal
Combined space stressors induce independent behavioral deficits predicted by early peripheral blood monocytes (flow cytometry)
National Aeronautics and Space Administration —
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to... -
Federal
Rodent Research-1 (RR1) NASA Validation Flight: Mouse liver transcriptomic, proteomic, epigenomic and histology data
National Aeronautics and Space Administration —
Translating fundamental biological discoveries from NASA Space Biology program into health risk from space flights has been an ongoing challenge. We propose to use... -
Federal
Persistence of Escherichia coli in the microbiomes of mizuna mustard (Brassica rapa var. japonica) - does seed sanitization matter?
National Aeronautics and Space Administration —
Seed sanitization via chemical processes removes/reduces microbes from the external surfaces of the seed and thereby could have an impact on the plants' health or... -
Federal
Quantitative evaluation of bioaerosols in different particle size fractions collected on the International Space Station (ISS)
National Aeronautics and Space Administration —
Exposure to bioaerosols can negatively impact human health. On the International Space Station (ISS) this exposure differs to that on Earth due to lack of... -
Federal
Microbial Observatory (ISS-MO): Indoor microbiome study of the International Space Station surfaces
National Aeronautics and Space Administration —
Presented here is the environmental microbiome study of the International Space Station surfaces. The environmental samples were collected with the polyester wipes... -
Federal
Gene-metabolite networks associated with impediment of bone fracture repair in spaceflight
National Aeronautics and Space Administration —
Adverse effects of spaceflight on musculoskeletal health increase the risk of bone injury and impairment of fracture healing. Its yet elusive molecular comprehension... -
Federal
Characterization of mouse ocular response to a 35-day spaceflight mission: Evidence of blood-retinal barrier disruption and ocular adaptations - Proteomics data
National Aeronautics and Space Administration —
The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was... -
Federal
Transcription profiling of S. cerevisiae cultures grown under low shear-modeled microgravity
National Aeronautics and Space Administration —
The goal of this study was to assess whether low shear-modeled microgravity (LSMMG) affects yeast genomic expression patterns using the powerful tool of whole genome... -
Federal
Microbial Observatory (ISS-MO): Microbial diversity
National Aeronautics and Space Administration —
The environmental microbiome study was designed to decipher microbial diversity of the International Space Station surfaces in terms of spatial and temporal... -
Federal
Altered Quorum Sensing and Physiology of Staphylococcus aureus During Spaceflight Detected by Multi-omics Data Analysis (BRIC-23: Secretomics)
National Aeronautics and Space Administration —
Staphylococcus aureus colonizes the nares of approximately 30% of humans, a risk factor for opportunistic infections. Because of the potential threat of S. aureus to... -
Federal
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Frontal Cortex
National Aeronautics and Space Administration —
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how... -
Federal
Combined space stressors induce independent behavioral deficits predicted by early peripheral blood monocytes (Behavioral Assays)
National Aeronautics and Space Administration —
Interplanetary space travel poses many hazards to the human body. To protect astronaut health and performance on critical missions, there is first a need to... -
Federal
Genomic Characterization and Virulence Potential of Two Fusarium oxysporum Isolates Cultured from the International Space Station
National Aeronautics and Space Administration —
Two isolates of Fusarium oxysporum, ISS-F3 and ISS-F4, were cultured from the dining table on the International Space Station (ISS). Genomic analyses using EF-1α...